Glutaminylglycine

Base Information

• Chemical Name: Glutaminylglycine
• CAS No.: 2650-65-9
• Molecular Formula: C7H13 N3 O4
• Molecular Weight: 203.198
• UNII: XWG2S6LG7H
• DSSTox Substance ID: DTXSID10426333
• Nikkaji Number: J749.465C
• Wikidata: Q27144172
• Metabolomics Workbench ID: 78763
• ChEMBL ID: CHEMBL90670
• Mol file: 2650-65-9.mol

Synonyms:Gln-Gly;glutaminyl-glycine;glutaminylglycine

Chemical Property of Glutaminylglycine

Chemical Property:

• Vapor Pressure: 9.33E-18mmHg at 25°C
• Melting Point: 163-165 °C
• Boiling Point: 635°Cat760mmHg
• PKA: 3.11±0.10(Predicted)
• Flash Point: 337.8°C
• PSA: 135.51000
• Density: 1.359g/cm³
• LogP: -0.42850
• Storage Temp.: -15°C
• XLogP3: -4.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 203.09060590
• Heavy Atom Count: 14
• Complexity: 241

Purity/Quality:

99%+, ^*data from raw suppliers

H-Gln-Gly-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)N)C(C(=O)NCC(=O)O)N
• Isomeric SMILES: C(CC(=O)N)[C@@H](C(=O)NCC(=O)O)N

Technology Process of Glutaminylglycine

There total 12 articles about Glutaminylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ H-Gln-Gly-OH (2650-65-9)

Guidance literature:

With palladium; acetic acid; Hydrogenation;

DOI:10.1021/ja01639a063

Reference yield:

Z-Glu(-NH2)-Gly-OBzl (57294-48-1) → H-Gln-Gly-OH (2650-65-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water;

Reference yield:

Cbz-L-Gln (2650-64-8) → H-Gln-Gly-OH (2650-65-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Ph₃P, CCl₄, Et₃N / acetonitrile

2: H₂ / Pd-C / methanol; H₂O

With tetrachloromethane; hydrogen; triethylamine; triphenylphosphine; palladium on activated charcoal; In methanol; water; acetonitrile;

upstream raw materials:

N-(N²-trityl-L-glutaminyl)-glycine

N-[N²-(toluene-4-sulfonyl)-L-glutaminyl]-glycine

Z-Glu(-NH₂)-Gly-OBzl

Trt-Gln

Downstream raw materials:

N-[(S)-5-oxopyrrolidin-2-ylcarbonyl]glycine