2-Propenoic acid, 3-phenyl-, octadecyl ester, (E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-phenyl-, octadecyl ester, (E)-
• CAS No.: 61415-12-1
• Molecular Formula: C27H44O2
• Molecular Weight: 400.645
• Mol file: 61415-12-1.mol

Synonyms:trans-octadecyl-3-phenylpropenoate;octadecyl cinnamate;trans-Zimtsaeure-octadecylester;n-octadecyl trans-cinnamate;octadecyl 3-phenylacrylate;

Chemical Property of 2-Propenoic acid, 3-phenyl-, octadecyl ester, (E)-

Chemical Property:

• Melting Point: 48-49 °C
• Boiling Point: 500.7±19.0 °C(Predicted)
• PSA: 26.30000
• Density: 0.929±0.06 g/cm3(Predicted)
• LogP: 8.50450

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-phenyl-, octadecyl ester, (E)-

There total 7 articles about 2-Propenoic acid, 3-phenyl-, octadecyl ester, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-octadecanol (112-92-5) + Methyl cinnamate (103-26-4,1754-62-7) → octadecyl (2E)-3-phenylprop-2-enoate (61415-12-1)

Guidance literature:

1-octadecanol; Methyl cinnamate; In xylene; for 0.5h; Heating;

With TiO(acac)2; In xylene; for 14h; Heating;

DOI:10.1021/jo0484878

Reference yield: 99.0%

1-octadecanol (112-92-5) + (E)-3-phenylacrylic acid (140-10-3) → octadecyl (2E)-3-phenylprop-2-enoate (61415-12-1)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃;

DOI:10.1248/cpb.57.476

Reference yield: 95.0%

2-((octadecyloxy)carbonyl)acetic acid (1002-31-9) + benzaldehyde (100-52-7) → octadecyl (2E)-3-phenylprop-2-enoate (61415-12-1)

Guidance literature:

With pyridine; 3-amino propanoic acid; Reflux;

DOI:10.1016/j.ejmech.2010.12.016

upstream raw materials:

1-octadecanol

Methyl cinnamate

(E)-3-phenylacrylic acid

2-((octadecyloxy)carbonyl)acetic acid

Downstream raw materials:

octadec-1-ene

(E)-3-phenylacrylic acid

α-Truxillsaeure-octadecylester

(1R,2R,3S,4S)-3,4-Diphenyl-cyclobutane-1,2-dicarboxylic acid dioctadecyl ester

Refernces

• 1、 Menezes, Jose C.J.M.D.S.,Kamat, Shrivallabh P.,Cavaleiro, Jose A.S.,Gaspar, Alexandra,Garrido, Jorge,Borges, Fernanda. "Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates". . p. 773 - 777. Retrieved 2011/03/19.
• 2、 Chen, Chien-Tien,Kuo, Jen-Huang,Ku, Cheng-Hsiu,Weng, Shiue-Shien,Liu, Cheng-Yuan. "Nucleophilic acyl substitutions of esters with protic nucleophiles mediated by amphoteric, oxotitanium, and vanadyl species". . p. 1328 - 1339. Retrieved 2007/10/03.