2,3-Diphenyl-2H-azirine

Base Information

• Chemical Name: 2,3-Diphenyl-2H-azirine
• CAS No.: 16483-98-0
• Molecular Formula: C14H11 N
• Molecular Weight: 193.248
• Hs Code.: 2933990090
• NSC Number: 122775
• Nikkaji Number: J113.733F
• Mol file: 16483-98-0.mol

Synonyms:2,3-Diphenyl-2H-azirine;16483-98-0;2H-Azirine, 2,3-diphenyl-;2,3-Diphenyl-3H-azirine;NSC122775;2,3-Diphenylazirine;2H-Azirine,3-diphenyl-;TimTec1_004918;SCHEMBL10945637;HMS1547P12;NSC 122775;NSC-122775

Chemical Property of 2,3-Diphenyl-2H-azirine

Chemical Property:

• Vapor Pressure: 0.000506mmHg at 25°C
• Boiling Point: 323.1°Cat760mmHg
• PKA: 3.16±0.40(Predicted)
• Flash Point: 141.3°C
• PSA: 12.36000
• Density: 1.09g/cm³
• LogP: 2.66620
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 193.089149355
• Heavy Atom Count: 15
• Complexity: 244

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2C(=N2)C3=CC=CC=C3

Technology Process of 2,3-Diphenyl-2H-azirine

There total 26 articles about 2,3-Diphenyl-2H-azirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(Z)-(1-azidoethene-1,2-diyl)dibenzene (4098-18-4) → 2,3-diphenyl-2H-azirine (16483-98-0)

Guidance literature:

at 130 ℃; for 0.266667h; under 6000.6 Torr; Green chemistry;

DOI:10.3762/BJOC.17.20

Reference yield: 93.0%

1,2-diphenylethanone O-acetyl oxime (19690-01-8) → 2,3-diphenyl-2H-azirine (16483-98-0)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;

DOI:10.1039/c8ob00923f

Reference yield: 85.0%

1,2-diphenylethanoneoxime tert-butyl carbonate → 2,3-diphenyl-2H-azirine (16483-98-0)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃; Inert atmosphere;

DOI:10.1039/c8ob00923f

upstream raw materials:

2,3-Diphenylthiirene 1,1-dioxide

(Z)-(1-azidoethene-1,2-diyl)dibenzene

N-(4,5-diphenyl-[1,2,3]triazol-1-yl)-benzamide

N-(4,5-diphenyl-1H-[1,2,3]triazol-1-yl)-4-methyl-benzamide

Downstream raw materials:

1t,3,8,8a-tetraphenyl-(8at)-1,3,8,8a-tetrahydro-3r,8c-epioxido-azirino[1,2-b]isoquinoline

5-(tert-butyl)-2,4-diphenyloxazole

5-(p-Chlorphenyl)-2,4-diphenyl-3-oxazolin.

5-(p-Chlorphenyl)-2,4-diphenyl-3-oxazolin.

Refernces

• 1、 Andresini, Michael,Degannaro, Leonardo,Luisi, Renzo. "A sustainable strategy for the straightforward preparation of 2H-azirines and highly functionalized NH-aziridines from vinyl azides using a single solvent flow-batch approach". supporting information. p. 203 - 209. Retrieved 2021/02/26.
• 2、 Wang, Zaibin,Li, Hanjie,Wang, Zhichao,Suleman, Muhammad,Wang, Yanguang,Lu, Ping. "Photocatalytic Approach for Construction of 5,6-Dihydroimidazo[2,1- A[isoquinolines and Their Luminescent Properties". . p. 8101 - 8111. Retrieved 2021/06/28.