Ethyl methyl phenylphosphonate

Base Information

• Chemical Name: Ethyl methyl phenylphosphonate
• CAS No.: 61733-60-6
• Molecular Formula: C9H13O3P
• Molecular Weight: 200.174
• DSSTox Substance ID: DTXSID60505182
• Nikkaji Number: J3.032.905H
• Mol file: 61733-60-6.mol

Synonyms:Ethyl methyl phenylphosphonate;61733-60-6;SCHEMBL18261810;DTXSID60505182

Chemical Property of Ethyl methyl phenylphosphonate

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 200.06023127
• Heavy Atom Count: 13
• Complexity: 187

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOP(=O)(C1=CC=CC=C1)OC

Technology Process of Ethyl methyl phenylphosphonate

There total 56 articles about Ethyl methyl phenylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methanol (67-56-1) + ethyl Phenylphosphinate (172487-18-2,2511-09-3) → ethyl methyl phenylphosphonate (61733-60-6)

Guidance literature:

With 1-methyl-1H-imidazole; tetrachloromethane; at 26 ℃; Reagent/catalyst;

DOI:10.1002/hc.21204

Reference yield: 81.0%

methanol (67-56-1) + ethyl hydrogen phenylphosphonate (4546-19-4) → ethyl methyl phenylphosphonate (61733-60-6)

Guidance literature:

With copper(l) iodide; sodium carbonate; triethylamine; In tetrachloromethane; at 80 ℃; for 12h;

DOI:10.1021/cs501523g

Reference yield: 81.0%

(S)-(-)-O-Methyl S-methyl phenylphosphonothioate (77326-05-7) → (R)-O-ethyl O-methyl phenylphosphonothioate (61733-60-6,78177-48-7,92470-70-7,77314-08-0)

Guidance literature:

With silver nitrate; In ethanol; for 15h; Ambient temperature;

DOI:10.1021/ja00197a056

upstream raw materials:

ethanol

1-(methoxy-phenyl-phosphinoyl)-5-phenyl-1H-pyrazole-3-carboxylic acid methyl ester

P,P-dichlorophenylphosphine oxide

methanol

Refernces

• 1、 Xiong, Biquan,Feng, Xiaofeng,Zhu, Longzhi,Chen, Tieqiao,Zhou, Yongbo,Au, Chak-Tong,Yin, Shuang-Feng. "Direct aerobic oxidative esterification and arylation of P(O)-OH compounds with alcohols and diaryliodonium triflates". . p. 537 - 543. Retrieved 2015/04/14.
• 2、 Crenshaw, Michael D.. "Synthesis of alkyl- and arylphosphonic acid monoesters by direct esterification of dibasic phosphonic acids in the presence of an arsonic acid catalyst". . p. 1509 - 1516. Retrieved 2007/10/03.