7H-Pyrido[3,4-c]carbazole

Base Information

• Chemical Name: 7H-Pyrido[3,4-c]carbazole
• CAS No.: 205-27-6
• Molecular Formula: C15H10N2
• Molecular Weight: 218.2533
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID40942672
• Nikkaji Number: J1.574.859A
• Wikidata: Q82919678
• ChEMBL ID: CHEMBL304513
• Mol file: 205-27-6.mol

Synonyms:7H-Pyrido[3,4-c]carbazole;7H-Pyrido(3,4-c)carbazole;205-27-6;carbazole deriv. 16;pyrido[3,4-c]carbazole;BDBM6956;CHEMBL304513;SCHEMBL8120408;DTXSID40942672;5,11-diazatetracyclo[8.7.0.0;{2,7}.0;{12,17}]heptadeca-1,3,5,7,9,12,14,16-octaene

Chemical Property of 7H-Pyrido[3,4-c]carbazole

Chemical Property:

• Vapor Pressure: 3.21E-09mmHg at 25°C
• Melting Point: 245-246 °C(Solv: acetone (67-64-1))
• Boiling Point: 488.6°Cat760mmHg
• PKA: 15.82±0.30(Predicted)
• Flash Point: 229.1°C
• PSA: 28.68000
• Density: 1.336g/cm³
• LogP: 3.86930
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 218.084398327
• Heavy Atom Count: 17
• Complexity: 291

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(N2)C=CC4=C3C=CN=C4

Technology Process of 7H-Pyrido[3,4-c]carbazole

There total 4 articles about 7H-Pyrido[3,4-c]carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-carbazol-4-yl-ethyl)-formamide → 7H-pyrido<3,4-c>carbazole (205-27-6)

Guidance literature:

With formic acid ethyl ester; trichlorophosphate; benzene; Dehydrieren des Reaktionsprodukts an Platin bei 200grad;

DOI:10.1021/ja01167a046

Reference yield:

2-carbazol-4-yl-ethylamine (854822-52-9) → 7H-pyrido<3,4-c>carbazole (205-27-6)

Guidance literature:

Multi-step reaction with 2 steps

2: ethyl formate; POCl₃; benzene / Dehydrieren des Reaktionsprodukts an Platin bei 200grad

With formic acid ethyl ester; trichlorophosphate; benzene;

DOI:10.1021/ja01167a046

Reference yield:

5-amino-7H-pyrido<3,4-c>carbazole → 7H-pyrido<3,4-c>carbazole (205-27-6)

Guidance literature:

With hydrogenchloride; hypophosphorous acid; sodium nitrite; Yield given. Multistep reaction; 1.) water, 10 deg C, 2 h, 2.) 25 deg C, 16 h;

upstream raw materials:

2-carbazol-4-yl-ethylamine

Refernces

• 1、 Bergman, Jan,Goonewardena, Harris. "A Reinvestigation of Stillwell's Synthesis of 6H-Pyridocarbazoles". . p. 763 - 766. Retrieved 2007/10/02.