4-Pyridinecarboxylic acid, 2-chloro-6-methoxy-, hydrazide

Base Information

• Chemical Name: 4-Pyridinecarboxylic acid, 2-chloro-6-methoxy-, hydrazide
• CAS No.: 61832-07-3
• Molecular Formula: C7H8ClN3O2
• Molecular Weight: 201.612
• Mol file: 61832-07-3.mol

Synonyms:

Chemical Property of 4-Pyridinecarboxylic acid, 2-chloro-6-methoxy-, hydrazide

Chemical Property:

• PSA: 77.24000
• LogP: 1.43830

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Pyridinecarboxylic acid, 2-chloro-6-methoxy-, hydrazide

There total 1 articles about 4-Pyridinecarboxylic acid, 2-chloro-6-methoxy-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dichloropyridine-4-carboxylic acid (5398-44-7) → 2-chloro-6-methoxyisonicotinohydrazide (61832-07-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 120 - 130 °C

2: concentrated H₂SO₄

3: aqueous ethanol; N₂H₄+H₂O

With ethanol; sulfuric acid; hydrazine hydrate;

Reference yield:

2-chloro-6-methoxyisonicotinohydrazide (61832-07-3) → 2-methoxy-isonicotinic acid hydrazide (19353-97-0)

Guidance literature:

With hydrogen; triethylamine; palladium 10% on activated carbon; In ethanol; at 20 ℃;

upstream raw materials:

2,6-dichloropyridine-4-carboxylic acid

Downstream raw materials:

2-methoxy-isonicotinic acid hydrazide