N-(3,4-Dichlorophenyl)-N'-hydroxypropanediamide

Base Information

• Chemical Name: N-(3,4-Dichlorophenyl)-N'-hydroxypropanediamide
• CAS No.: 65051-16-3
• Molecular Formula: C9H8 Cl2 N2 O3
• Molecular Weight: 263.08
• DSSTox Substance ID: DTXSID20215376
• Wikidata: Q83091413
• Mol file: 65051-16-3.mol

Synonyms:N-(3,4-Dichlorophenyl)-N'-hydroxypropanediamide;CRL 40,491;65051-16-3;3,4-Dichlorophenylcarbamoylacetohydroxamic acid;Propanediamide, N-(3,4-dichlorophenyl)-N'-hydroxy-;SCHEMBL11435817;DTXSID20215376;LS-119705

Chemical Property of N-(3,4-Dichlorophenyl)-N'-hydroxypropanediamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.581g/cm³
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 261.9911975
• Heavy Atom Count: 16
• Complexity: 276

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1NC(=O)CC(=O)NO)Cl)Cl
• Use Description: Propanediamide, N1-(3,4-dichlorophenyl)-N3-hydroxy-, is a chemical compound with applications in various fields. In the field of pharmaceuticals and medicine, it can serve as an intermediate compound in the synthesis of potential drug candidates, particularly those targeting specific medical conditions. Its role is pivotal in drug development, contributing to the creation of novel medications and therapeutic agents. Additionally, in the realm of chemical research and organic synthesis, this compound can be employed as a building block for the creation of complex organic molecules, aiding in the development of new synthetic pathways and the study of chemical reactions. Furthermore, in academic and industrial laboratories, it may be used as a reference compound for the investigation of amides and their reactivity, contributing to the advancement of chemical research and understanding. Its multifaceted utility underscores its significance in advancing pharmaceuticals, organic chemistry, and scientific investigation, where it plays a crucial role in drug discovery, compound synthesis, and chemical analysis.

Technology Process of N-(3,4-Dichlorophenyl)-N'-hydroxypropanediamide

There total 3 articles about N-(3,4-Dichlorophenyl)-N'-hydroxypropanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H9Cl2NO3 → 3.4-Dichlorphenylcarbamoylacetohydroxamsaeure (65051-16-3)

Guidance literature:

With hydroxylamine; N-ethyl-N,N-diisopropylamine; In methanol; at 20 ℃; for 24h; Reflux;

DOI:10.1021/acschembio.8b00257

Reference yield:

ethyl 3-((3,4-dichlorophenyl)amino)-3-oxopropanoate (15386-79-5) → 3.4-Dichlorphenylcarbamoylacetohydroxamsaeure (65051-16-3)

Guidance literature:

With hydroxylamine;

Reference yield:

→ 3.4-Dichlorphenylcarbamoylacetohydroxamsaeure (65051-16-3)

Guidance literature:

Entspr. Et-Ester, NH2OH;

upstream raw materials:

ethyl 3-((3,4-dichlorophenyl)amino)-3-oxopropanoate

Refernces