2,3-Dichloro-6-methylaniline

Base Information

• Chemical Name: 2,3-Dichloro-6-methylaniline
• CAS No.: 62077-27-4
• Molecular Formula: C7H7Cl2N
• Molecular Weight: 176.04300
• Hs Code.: 2921430090
• DSSTox Substance ID: DTXSID10556740
• Wikidata: Q82438416
• Mol file: 62077-27-4.mol

Synonyms:2,3-Dichloro-6-methylaniline;62077-27-4;Benzenamine, 2,3-dichloro-6-methyl-;2,3-dichloro-6-methyl aniline;SCHEMBL10417671;DTXSID10556740;KSJUCTMXLJIVIE-UHFFFAOYSA-N;MFCD11878133;AKOS024259809;BS-18927;SY250603;CS-0313949;A936183

Chemical Property of 2,3-Dichloro-6-methylaniline

Chemical Property:

• Melting Point: 33 °C
• Boiling Point: 288-290 °C(Press: 739 Torr)
• PKA: 1.45±0.10(Predicted)
• PSA: 26.02000
• Density: 1.334±0.06 g/cm3(Predicted)
• LogP: 3.46520
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 174.9955546
• Heavy Atom Count: 10
• Complexity: 118

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dichloro-6-methylaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=C(C=C1)Cl)Cl)N

Technology Process of 2,3-Dichloro-6-methylaniline

There total 2 articles about 2,3-Dichloro-6-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-(2,3-dichloro-6-methylphenyl)-2,2-dimethylpropanamide (1019332-47-8) → 2,3-dichloro-6-methyl aniline (62077-27-4)

Guidance literature:

With potassium hydroxide; In ethylene glycol; at 170 ℃; for 7h;

DOI:10.1016/j.bmc.2007.10.100

Reference yield:

4-bromo-2,3-dichloro-6-methyl aniline → 2,3-dichloro-6-methyl aniline (62077-27-4)

Guidance literature:

With sodium acetate; palladium; In acetic acid ethanol;

Reference yield:

2,3-dichloro-6-methyl aniline (62077-27-4) + potassium o-bromobenzoate (16497-87-3) → 2-(2,3-Dichloro-6-methyl-phenylamino)-benzoic acid

Guidance literature:

With N-ethylmorpholine;; copper diacetate; In N,N-dimethyl-formamide; at 145 ℃; for 3h;

upstream raw materials:

N-(2,3-dichloro-6-methylphenyl)-2,2-dimethylpropanamide

Refernces

• 1、 -. "Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil". . . Retrieved 2008/06/13.
• 2、 -. "Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn". . . Retrieved 2008/06/13.