2-oxo-2H-chromen-4-yl methanesulfonate

Base Information

• Chemical Name: 2-oxo-2H-chromen-4-yl methanesulfonate
• CAS No.: 62113-90-0
• Molecular Formula: C10H8O5S
• Molecular Weight: 240.237
• Mol file: 62113-90-0.mol

Synonyms:

Chemical Property of 2-oxo-2H-chromen-4-yl methanesulfonate

Chemical Property:

• Vapor Pressure: 2.91E-08mmHg at 25°C
• Boiling Point: 449.2°Cat760mmHg
• Flash Point: 225.5°C
• Density: 1.5g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-oxo-2H-chromen-4-yl methanesulfonate

There total 2 articles about 2-oxo-2H-chromen-4-yl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + methanesulfonyl chloride (124-63-0) → 2-oxo-2H-chromen-4-yl methanesulfonate (62113-90-0)

Guidance literature:

With triethylamine; In ethyl acetate; at 0 - 20 ℃; for 0.166667h; Green chemistry;

DOI:10.1055/s-0034-1378867

Reference yield: 80.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + 1-(methylsulfonyl)-4-phenyl-1H-1,2,3-triazole (1135539-10-4) → 2-oxo-2H-chromen-4-yl methanesulfonate (62113-90-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In 1,2-dichloro-ethane; at 90 ℃; for 5h;

DOI:10.1080/00397911.2019.1582065

Reference yield: 85.0%

2-oxo-2H-chromen-4-yl methanesulfonate (62113-90-0) + 2-bromo-5-methoxy-benzaldehyde (7507-86-0) → 5-methoxy-2-(2-oxo-2H-chromen-4-yl)-benzaldehyde

Guidance literature:

With triphenylphosphine; zinc; bis(triphenylphosphine)nickel(II) chloride; In toluene; at 90 ℃; for 2h;

DOI:10.1055/s-2004-832818

upstream raw materials:

4-hydroxy[1]benzopyran-2-one

methanesulfonyl chloride

1-(methylsulfonyl)-4-phenyl-1H-1,2,3-triazole

Downstream raw materials:

4,4′-dimethoxy[1,1′-biphenyl]-2,2′-dicarbaldehyde

4,4'-bis-(2H-chromen-2-one)

4-phenylcoumarin

4-(4-methoxybenzoyl)-2H-chromen-2-one

Refernces

• 1、 He, Xinwei,Wu, Yuhao,Zuo, Youpeng,Xie, Mengqing,Li, Ruxue,Shang, Yongjia. "Transition metal- and oxidant-free sulfonylation of 1-sulfonyl-1H-1,2,3-triazoles to enols for the synthesis of sulfonate derivatives". supporting information. p. 959 - 972. Retrieved 2019/03/14.
• 2、 Lei, Xiangyang,Jalla, Anusha,Abou Shama, Mhd A.,Stafford, Jamie M.,Cao, Billy. "Chromatography-Free and Eco-Friendly Synthesis of Aryl Tosylates and Mesylates". supporting information. p. 2578 - 2585. Retrieved 2015/09/01.