(3R)-1,1-dimethoxynonan-3-ol

Base Information

• Chemical Name: (3R)-1,1-dimethoxynonan-3-ol
• CAS No.: 272122-72-2
• Molecular Formula: C₁₁H₂₄O₃
• Molecular Weight: 204.31
• DSSTox Substance ID: DTXSID60370372
• Nikkaji Number: J1.289.532A
• Wikidata: Q82157560
• Mol file: 272122-72-2.mol

Synonyms:(3R)-1,1-dimethoxynonan-3-ol;272122-72-2;(3R)-1,1-dimethoxy-3-nonanol;(R)-(-)-3-hydroxynonanal dimethyl acetal;(R)-1,1-Dimethoxy-3-nonanol;DTXSID60370372;(R)-3-hydroxynonanal dimethylacetal;AKOS017343271;A818957

Chemical Property of (3R)-1,1-dimethoxynonan-3-ol

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 0.000274mmHg at 25°C
• Refractive Index: 1.437
• Boiling Point: 287.6 °C at 760 mmHg
• PKA: 15.26±0.20(Predicted)
• Flash Point: 127.8 °C
• PSA: 38.69000
• Density: 0.924 g/cm³
• LogP: 2.32670
• Storage Temp.: Refrigerator (+4°C)
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 204.17254462
• Heavy Atom Count: 14
• Complexity: 113

Purity/Quality:

99% ^*data from raw suppliers

(R)-(-)-3-HYDROXYNONANAL DIMETHYL ACETAL 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCC(CC(OC)OC)O
• Isomeric SMILES: CCCCCC[C@H](CC(OC)OC)O

Technology Process of (3R)-1,1-dimethoxynonan-3-ol

There total 4 articles about (3R)-1,1-dimethoxynonan-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + glyceryl tri-(12R)-hydroxy-((9Z)-octadecanoate) → (R)-3-hydroxynonanal dimethyl acetal (272122-72-2)

Guidance literature:

glyceryl tri-(12R)-hydroxy-((9Z)-octadecanoate); With ozone; In dichloromethane; at 0 ℃;

With hydroxylamine hydrochloride; In dichloromethane; for 10h; Heating;

methanol; With toluene-4-sulfonic acid; for 6h; Further stages.; Heating;

DOI:10.1134/S1070428007080039

Reference yield: 74.0%

methanol (67-56-1) + methyl ricinoleate (141-24-2) → (R)-3-hydroxynonanal dimethyl acetal (272122-72-2)

Guidance literature:

With hydrogenchloride; ozone; for 5h;

DOI:10.1007/s00044-019-02348-y

Reference yield:

methanol (67-56-1) + methyl ricinoleate (141-24-2) → 9,9-bis(methoxy)nonanoic acid methyl ester (1599-48-0) + (R)-3-hydroxynonanal dimethyl acetal (272122-72-2)

Guidance literature:

methyl ricinoleate; With sodium periodate; In methanol; for 15h;

methanol; With toluene-4-sulfonic acid; at 40 ℃; for 1.5h;

DOI:10.1021/ja038814d

upstream raw materials:

(R)-3-hydroxynonanal

methanol

methyl ricinoleate

Refernces

• 1、 Matysiak, Sylwia,Kula, Józef,B?aszczyk, Alina. "Chiral amide derivatives of ricinoleic acid and 3-hydroxynonanoic acid synthesis and cytotoxic activity". . p. 948 - 958. Retrieved 2019.
• 2、 Ishmuratov,Shayakhmetova,Yakovleva,Legostaeva,Shitikova,Galkin,Tolstikov. "Ozonolysis of alkenes and study of reactions of polyfunctional compounds: LXVIII. Investigation of transformations of peroxide products of olefins ozonolysis treated with hydroxylamine hydrochloride". . p. 1114 - 1119. Retrieved 2008/03/11.