(3R,4R)-7-methyl-3,4-dihydrotetraphene-3,4-diol

Base Information

• Chemical Name: (3R,4R)-7-methyl-3,4-dihydrotetraphene-3,4-diol
• CAS No.: 64521-14-8
• Molecular Formula: C₁₉H₁₆O₂
• Molecular Weight: 276.335
• Mol file: 64521-14-8.mol

Synonyms:Benz[a]anthracene-3,4-diol,3,4-dihydro-7-methyl-, trans-; trans-3,4-Dihydroxy-3,4-dihydro-7-methylbenz[a]anthracene;trans-7-Methylbenz[a]anthracene-3,4-dihydrodiol

Chemical Property of (3R,4R)-7-methyl-3,4-dihydrotetraphene-3,4-diol

Chemical Property:

• Vapor Pressure: 3.13E-12mmHg at 25°C
• Boiling Point: 533.9°Cat760mmHg
• Flash Point: 258.3°C
• Density: 1.328g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3R,4R)-7-methyl-3,4-dihydrotetraphene-3,4-diol

There total 10 articles about (3R,4R)-7-methyl-3,4-dihydrotetraphene-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

7-methylbenzanthracene-3,4-dione (71989-02-1) → (+/-)-trans-3,4-Dihydroxy-3,4-dihydro-7-methylbenzanthracene (64521-14-8,62641-70-7,74634-54-1,88244-38-6)

Guidance literature:

With sodium tetrahydroborate; oxygen; In ethanol;

DOI:10.1021/jm00396a023

Reference yield:

3-methoxy-7-methylbenzanthracene (71988-99-3) → (+/-)-trans-3,4-Dihydroxy-3,4-dihydro-7-methylbenzanthracene (64521-14-8,62641-70-7,74634-54-1,88244-38-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / HBr / acetic acid / Heating

2: 87 percent / Adogen 464, Fremy's salt, KH₂PO₄ / benzene; CH₂Cl₂; H₂O

3: 96 percent / NaBH₄, O₂ / ethanol

With sodium tetrahydroborate; potassium dihydrogenphosphate; adogen 464; potassiuim nitrosodisulfonate; hydrogen bromide; oxygen; In ethanol; dichloromethane; water; acetic acid; benzene;

DOI:10.1021/jm00396a023

Reference yield:

12-acetoxy-3-methoxy-7-methylbenzanthracene (71988-98-2) → (+/-)-trans-3,4-Dihydroxy-3,4-dihydro-7-methylbenzanthracene (64521-14-8,62641-70-7,74634-54-1,88244-38-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 91 percent / HI, H₃PO₂ / acetic acid / 100 °C

2: 93 percent / HBr / acetic acid / Heating

3: 87 percent / Adogen 464, Fremy's salt, KH₂PO₄ / benzene; CH₂Cl₂; H₂O

4: 96 percent / NaBH₄, O₂ / ethanol

With sodium tetrahydroborate; potassium dihydrogenphosphate; adogen 464; potassiuim nitrosodisulfonate; hydrogen bromide; hydrogen iodide; oxygen; hypophosphorous acid; In ethanol; dichloromethane; water; acetic acid; benzene;

DOI:10.1021/jm00396a023

upstream raw materials:

7-methylbenzanthracene-3,4-dione

3-methoxy-7-methylbenzanthracene

12-acetoxy-3-methoxy-7-methylbenzanthracene

3-hydroxy-7-methylbenzanthracene

Refernces