6-METHYL-5-PROPYL-4(1H)-PYRIMIDINONE

Base Information

• Chemical Name: 6-METHYL-5-PROPYL-4(1H)-PYRIMIDINONE
• CAS No.: 103980-68-3
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.196
• Hs Code.: 2933599090
• Mol file: 103980-68-3.mol

Synonyms:4(1H)-Pyrimidinone,6-methyl-5-propyl- (9CI); 5-Propyl-6-methylpyrimidin-4-one

Chemical Property of 6-METHYL-5-PROPYL-4(1H)-PYRIMIDINONE

Chemical Property:

• Vapor Pressure: 0.0409mmHg at 25°C
• Melting Point: 119-123 °C(lit.)
• Boiling Point: 239.1°Cat760mmHg
• Flash Point: 98.4°C
• PSA: 46.01000
• Density: 1.1g/cm³
• LogP: 1.44310
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-Methyl-5-propyl-4(1H)-pyrimidinone ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 6-Methyl-5-propyl-4(1H)-pyrimidinone is used in preparation of Oxadiazole compound as agricultural and horticultural fungicide.

Technology Process of 6-METHYL-5-PROPYL-4(1H)-PYRIMIDINONE

There total 4 articles about 6-METHYL-5-PROPYL-4(1H)-PYRIMIDINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl α-propylacetoacetate (130000-32-7) + formamidine (463-52-5) → 5-Propyl-6-methyl-pyrimidin-4-one (103980-68-3)

Guidance literature:

formamidine; With sodium methylate; In methanol; at 20 ℃; for 0.25h;

methyl α-propylacetoacetate; at 20 ℃;

Reference yield:

methyl α-propylacetoacetate (130000-32-7) + formamidine (463-52-5) → 6-methyl-5-propyl-3H-pyrimidin-4-one (103980-68-3)

Guidance literature:

formamidine; With sodium methylate; In methanol; at 20 ℃; for 0.25h;

methyl α-propylacetoacetate; In methanol; at 20 ℃;

Reference yield:

6-methyl-5-propyl-2-thiouracil (51482-41-8) → 6-methyl-5-propyl-3H-pyrimidin-4-one (103980-68-3)

Guidance literature:

With water;

DOI:10.1021/jo01130a003

upstream raw materials:

6-methyl-5-propyl-2-thiouracil

ethyl 2-propylacetoacetate

methyl α-propylacetoacetate

formamidine

Refernces

• 1、 -. "ARYL ACID PYRIMIDINYL METHYL AMIDES, PYRIDAZINYL METHYL AMIDES AND RELATED COMPOUNDS". Page 54. . Retrieved 2010/02/08.