1-phenyl-N-(tritylsulfanyl)methanamine

Base Information

• Chemical Name: 1-phenyl-N-(tritylsulfanyl)methanamine
• CAS No.: 86864-57-5
• Molecular Formula: C26H23NS
• Molecular Weight: 381.5325
• Mol file: 86864-57-5.mol

Synonyms:

Chemical Property of 1-phenyl-N-(tritylsulfanyl)methanamine

Chemical Property:

• Vapor Pressure: 4.03E-11mmHg at 25°C
• Boiling Point: 525.1°Cat760mmHg
• Flash Point: 271.4°C
• Density: 1.146g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenyl-N-(tritylsulfanyl)methanamine

There total 5 articles about 1-phenyl-N-(tritylsulfanyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

tritylsulfenyl chloride (24165-03-5) + benzylamine (100-46-9) → N-Benzyl-1,1,1-triphenylmethanesulfenamide (86864-57-5)

Guidance literature:

With sodium carbonate; In tetrahydrofuran;

DOI:10.1021/jo00168a032

Reference yield: 97.0%

Benzaldehyde tritylsulfenimine (86864-34-8) → N-Benzyl-1,1,1-triphenylmethanesulfenamide (86864-57-5)

Guidance literature:

With sodium cyanoborohydride; trifluoroacetic acid; In tetrahydrofuran; Ambient temperature; pH 4-5, indicator Bromocresol Green or pH 5-6, indicator Chlorophenol Red;

DOI:10.1021/jo00168a031

Reference yield:

triphenylmethanethiol (3695-77-0) → N-Benzyl-1,1,1-triphenylmethanesulfenamide (86864-57-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 88 percent / Sulfuryl chloride / toluene; diethyl ether / 2 h / 0 °C

2: 78 percent / 29 percent NH₄OH/H₂O / CH₂Cl₂ / 0 °C

3: 99 percent / Pyridinium p-toluenesulfonate, (PPTS)/anhydr. MgSO₄ / CH₂Cl₂ / 2 h / Ambient temperature

4: 97 percent / NaBH₃CN/1percent CF₃COOH / tetrahydrofuran / Ambient temperature; pH 4-5, indicator Bromocresol Green or pH 5-6, indicator Chlorophenol Red

With ammonium hydroxide; sulfuryl dichloride; water; pyridinium p-toluenesulfonate; sodium cyanoborohydride; magnesium sulfate; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane; toluene;

DOI:10.1021/jo00168a031

upstream raw materials:

Benzaldehyde tritylsulfenimine

tritylsulfenyl chloride

benzylamine

triphenylmethanethiol

Downstream raw materials:

Triphenylmethylethylether

1-benzyl-3-phenylthiourea

Refernces

• 1、 Branchaud, Bruce P.. "Studies on the Preparation and Reactions of Tritylsulfenimines". . p. 3531 - 3538. Retrieved 2007/10/02.