2-Methyl-3-pentanol

Base Information

• Chemical Name: 2-Methyl-3-pentanol
• CAS No.: 565-67-3
• Molecular Formula: C6H14 O
• Molecular Weight: 102.177
• European Community (EC) Number: 209-286-3
• UNII: PVA5FLE5K2
• DSSTox Substance ID: DTXSID70870616
• Nikkaji Number: J49.948J
• Wikipedia: 2-Methyl-3-pentanol
• Wikidata: Q3278285
• Mol file: 565-67-3.mol

Synonyms:2-METHYL-3-PENTANOL;2-Methylpentan-3-ol;565-67-3;3-Pentanol, 2-methyl-;Propanol, 1-isopropyl-;BRN 1718952;2-Methyl-pentan-3-ol;EINECS 209-286-3;PVA5FLE5K2;2-Methyl-3-pentanol, (+/-)-;4-01-00-01716 (Beilstein Handbook Reference);4-Methyl-3-pentanol;UNII-PVA5FLE5K2;DL-4-Methylpentan-3-ol;SCHEMBL85852;(+/-)-2-Methyl-3-pentanol;ISTJMQSHILQAEC-UHFFFAOYSA-;DTXSID70870616;2-Methyl-3-pentanol, >=99%;MFCD00004567;AKOS009159110;(+/-)-4-METHYL-3-PENTANOL;1-ETHYL-2-METHYLPROPYL ALCOHOL;LS-101902;FT-0612953;EN300-140250;Q3278285;Z445987082

Chemical Property of 2-Methyl-3-pentanol

Chemical Property:

• Appearance/Colour: CLEAR COLOURLESS LIQUID
• Vapor Pressure: 5.35mmHg at 25°C
• Melting Point: -48.42°C (estimate)
• Refractive Index: n20/D 1.417(lit.)
• Boiling Point: 126.5°Cat760mmHg
• PKA: 15.17±0.20(Predicted)
• Flash Point: 46.1°C
• PSA: 20.23000
• Density: 0.811g/cm³
• LogP: 1.41330
• Water Solubility.: Amalgamate with ethanol, ethyl ether, benzene. Insoluble in water
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 102.104465066
• Heavy Atom Count: 7
• Complexity: 41.4

Purity/Quality:

99% ^*data from raw suppliers

2-Methylpentan-3-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi:Irritant
• Statements: 10
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Alcohols (
• Canonical SMILES: CCC(C(C)C)O
• Uses: 2-Methyl-3-pentanol (Ethyl isopropyl carbinol) was used as a volatile marker.

Technology Process of 2-Methyl-3-pentanol

There total 32 articles about 2-Methyl-3-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

ethyl isopropyl ketone (565-69-5) → 2-methyl-3-pentanol (565-67-3)

Guidance literature:

With tris(pentafluorophenyl)borate; hydrogen; In diethyl ether; at 70 ℃; for 12h; under 45603.1 Torr; Solvent; Glovebox;

DOI:10.1021/ja508829x

Reference yield: 87.0%

aminodi(2-methylpent-3-yl)borane → 2-methyl-3-pentanol (565-67-3)

Guidance literature:

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1039/c6cc06151f

Reference yield: 18.0%

diethylzinc (557-20-0) + isobutyraldehyde (78-84-2) → 2-methyl-3-pentanol (565-67-3)

Guidance literature:

diethylzinc; With (1R,2R)-1,2-bis([1,1'-biphenyl]-3-yl)ethane-1,2-diol; In hexane; toluene; at 20 ℃; for 0.333333h; Inert atmosphere;

isobutyraldehyde; In hexane; toluene; at 20 ℃; for 24h; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/chir.22617

upstream raw materials:

ethyl isopropyl ketone

isopropylmagnesium bromide

propionaldehyde

isopropylmagnesium chloride

Downstream raw materials:

2-methyl-2-pentene

2-Methyl-pentanthiol-(3)

2-methyl-2-phenylpentane

4-methyl-2-pentene

Refernces

• 1、 Liu, Qiang,Xu, Guoqiang,Wang, Zhendong,Liu, Xiaoran,Wang, Xicheng,Dong, Linlin,Mu, Xindong,Liu, Huizhou. "Iridium Clusters Encapsulated in Carbon Nanospheres as Nanocatalysts for Methylation of (Bio)Alcohols". . p. 4748 - 4755. Retrieved 2017/12/15.
• 2、 Ramachandran, P. Veeraraghavan,Drolet, Michael P.,Kulkarni, Ameya S.. "A non-dissociative open-flask hydroboration with ammonia borane: Ready synthesis of ammonia-trialkylboranes and aminodialkylboranes". supporting information. p. 11897 - 11900. Retrieved 2016/10/09.