4-amino-3,5-diethylphenol

Base Information

• Chemical Name: 4-amino-3,5-diethylphenol
• CAS No.: 108451-25-8
• Molecular Formula: C10H15 N O
• Molecular Weight: 165.2322
• Mol file: 108451-25-8.mol

Synonyms:2,6-Diethyl-4-hydroxyaniline;4-Amino-3,5-diethylphenol

Chemical Property of 4-amino-3,5-diethylphenol

Chemical Property:

• Vapor Pressure: 0.000121mmHg at 25°C
• Boiling Point: 325.5°Cat760mmHg
• PKA: 10.44±0.23(Predicted)
• Flash Point: 150.6°C
• PSA: 46.25000
• Density: 1.06g/cm³
• LogP: 2.68040

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-amino-3,5-diethylphenol

There total 5 articles about 4-amino-3,5-diethylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-diethyl-4-nitrosophenol (103028-90-6) → 4-amino-3,5-diethylphenol (108451-25-8)

Guidance literature:

With hydrogen; palladium; In tetrahydrofuran; for 3h; under 760 Torr;

DOI:10.1021/jf990087b

Reference yield:

3,5-diethylphenol (1197-34-8) → 4-amino-3,5-diethylphenol (108451-25-8)

Guidance literature:

Multi-step reaction with 2 steps

2: Na₂S₂O₄ / 65 °C

With sodium dithionite;

DOI:10.1016/S1383-5718(97)00163-0

Reference yield:

4-(2,6-diethyl-4-hydroxy-phenylazo)-benzenesulfonic acid → 4-amino-3,5-diethylphenol (108451-25-8)

Guidance literature:

With sodium dithionite; at 65 ℃;

DOI:10.1016/S1383-5718(97)00163-0

upstream raw materials:

4-diazobenzenesulfonic acid

3,5-diethylphenol

2,6-diethylaniline

3,5-diethyl-4-nitrosophenol

Downstream raw materials:

3,5-Diethyl-p-benzoquionone-4-imine

N-Chloroacetyl-3,5-diethyl-4-aminophenol

ethyl 5-(4-chloroacetamido-3,5-diethyl)phenoxypentanoate

5-(4-chloroacetamido-3,5-diethyl)phenoxypentanoic acid

Refernces

• 1、 Tessier,Clark. "Hapten design in the development of competitive enzyme-linked immunosorbent assays for genotoxic metabolites of alachlor". . p. 3925 - 3933. Retrieved 2007/10/03.