Diazene-1,2-dicarboxylic acid

Base Information

• Chemical Name: Diazene-1,2-dicarboxylic acid
• CAS No.: 504-89-2
• Molecular Formula: C2H2N2O4
• Molecular Weight: 118.05
• Mol file: 504-89-2.mol

Synonyms:1,2-Diazendicarbonsaeure;

Chemical Property of Diazene-1,2-dicarboxylic acid

Chemical Property:

• Boiling Point: 357.1±25.0 °C(Predicted)
• PKA: 0.75±0.41(Predicted)
• PSA: 99.32000
• Density: 1.87±0.1 g/cm3(Predicted)
• LogP: 0.79460

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diazene-1,2-dicarboxylic acid

There total 2 articles about Diazene-1,2-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3aR,4R,6S,6aS)-4-(tert-butoxymethyl)-2,2-dimethyltetrahydrospiro[cyclopenta[d] [1,3]dioxole-5,1'-cyclopropan]-6-ol (1314254-54-0) + 6-chloro-7H-purine (87-42-3,111055-92-6) → Azodicarbonsaeure (504-89-2) + C20H27ClN4O3 (1314254-55-1)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 8.5h; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.05.012

Reference yield:

Azodicarboxamid (123-77-3,97707-96-5) → Azodicarbonsaeure (504-89-2)

Guidance literature:

With potassium hydroxide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol; at 0 ℃; bei nachfolgender Behandlung;

Reference yield:

(S)-2,2-dimethyl-5-hydroxymethyl-valerolactone (140944-13-4) + azodicarboxylic acid (504-89-2) + 5-n-octyloxy-2-(4-hydroxyphenyl)-pyrimidine (104539-91-5) → (S)-2,2-dimethyl-5-[4'-(5'-octyloxy-2'-pyrimidinyl)phenoxymethyl]valerolactone (140943-90-4)

Guidance literature:

With triphenylphosphine; In benzene;

upstream raw materials:

Azodicarboxamid

(3aR,4R,6S,6aS)-4-(tert-butoxymethyl)-2,2-dimethyltetrahydrospiro[cyclopenta[d] [1,3]dioxole-5,1'-cyclopropan]-6-ol

6-chloro-7H-purine

Downstream raw materials:

(S)-2,2-dimethyl-5-[4'-(5'-octyloxy-2'-pyrimidinyl)phenoxymethyl]valerolactone

Refernces