2-[(Diphenylmethyl)sulfanyl]-N-hydroxyacetamide

Base Information

• Chemical Name: 2-[(Diphenylmethyl)sulfanyl]-N-hydroxyacetamide
• CAS No.: 63547-44-4
• Molecular Formula: C15H15NO2S
• Molecular Weight: 273.356
• Hs Code.: 2930909090
• Mol file: 63547-44-4.mol

Synonyms:diphenylmethylsulfanylhydroxyacetamide;2-[(diphenylmethyl)sulfanyl]-N-hydroxyacetamide;Acetamide,2-[(diphenylmethyl)thio]-N-hydroxy;

Chemical Property of 2-[(Diphenylmethyl)sulfanyl]-N-hydroxyacetamide

Chemical Property:

• Melting Point: 111～113℃
• PSA: 78.12000
• LogP: 3.85490

Purity/Quality:

98%min ^*data from raw suppliers

2-[(Diphenylmethyl)sulfanyl]-N-hydroxyacetamide >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(Diphenylmethyl)sulfanyl]-N-hydroxyacetamide

There total 4 articles about 2-[(Diphenylmethyl)sulfanyl]-N-hydroxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(diphenylmethyl)(ethyl acetate)sulfide (63547-23-9) → 2-benzhydrylsulfanyl-N-hydroxyacetamide (63547-44-4)

Guidance literature:

With potassium hydroxide; hydroxylamine hydrochloride; In methanol; for 0.25h;

DOI:10.1016/j.tetasy.2004.01.039

Reference yield:

(benzhydrylthio)acetic acid (63547-22-8) → 2-benzhydrylsulfanyl-N-hydroxyacetamide (63547-44-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / H₂SO₄ / Heating

2: 92 percent / hydroxylamine hydrochloride; KOH / methanol / 0.25 h

With potassium hydroxide; sulfuric acid; hydroxylamine hydrochloride; In methanol;

DOI:10.1016/j.tetasy.2004.01.039

Reference yield:

1,1-Diphenylmethanol (91-01-0) → 2-benzhydrylsulfanyl-N-hydroxyacetamide (63547-44-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / trifluoroacetic acid / 3 h / 20 °C

2: 99 percent / H₂SO₄ / Heating

3: 92 percent / hydroxylamine hydrochloride; KOH / methanol / 0.25 h

With potassium hydroxide; sulfuric acid; hydroxylamine hydrochloride; trifluoroacetic acid; In methanol;

DOI:10.1016/j.tetasy.2004.01.039

upstream raw materials:

(diphenylmethyl)(ethyl acetate)sulfide

1,1-Diphenylmethanol

(benzhydrylthio)acetic acid

Downstream raw materials:

adrafinil

Refernces