Acetic Acid 2-Vinylphenyl Ester

Base Information

• Chemical Name: Acetic Acid 2-Vinylphenyl Ester
• CAS No.: 63600-35-1
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Hs Code.: 2915390090
• European Community (EC) Number: 677-077-8
• DSSTox Substance ID: DTXSID30436616
• Nikkaji Number: J632.331F
• Wikidata: Q82251902
• Mol file: 63600-35-1.mol

Synonyms:2-vinylphenyl acetate;63600-35-1;Acetic Acid 2-Vinylphenyl Ester;(2-ethenylphenyl) Acetate;2-Acetoxystyrene;styrene acetate;acetic acid (2-ethenylphenyl) ester;2-ethynylbenzoic?acid;(2-ethenylphenyl) ethanoate;SCHEMBL58004;DTXSID30436616;Acetic acid 2-ethenylphenyl ester;MFCD02093430;AKOS009156549;CS-0135206;A834435;2-Vinylphenyl Acetate (stabilized with Phenothiazine);Acetic acid 2-vinylphenyl ester, stabilized with Phenothiazine

Chemical Property of Acetic Acid 2-Vinylphenyl Ester

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Refractive Index: 1.5350-1.5390
• Boiling Point: 246.752oC at 760 mmHg
• Flash Point: 94.497oC
• PSA: 26.30000
• Density: 1.07
• LogP: 2.25490
• Storage Temp.: 0-10°C
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 162.068079557
• Heavy Atom Count: 12
• Complexity: 175

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-VinylphenylAcetate ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=CC=CC=C1C=C

Technology Process of Acetic Acid 2-Vinylphenyl Ester

There total 11 articles about Acetic Acid 2-Vinylphenyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acetic anhydride (108-24-7) + 2-allylphenol (695-84-1) → 2-acetoxystyrene (63600-35-1)

Guidance literature:

samarium(III) trifluoromethanesulfonate; at 20 ℃; for 0.166667h;

DOI:10.1080/07328300801991245

Reference yield: 72.0%

Methyltriphenylphosphonium bromide (1779-49-3) + acetic anhydride (108-24-7) + salicylaldehyde (90-02-8) → 2-acetoxystyrene (63600-35-1)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 0 - 30 ℃; for 0.25h; Inert atmosphere;

salicylaldehyde; In tetrahydrofuran; at 0 - 30 ℃; Inert atmosphere;

acetic anhydride; With dmap; triethylamine; In tetrahydrofuran; dichloromethane; at 0 - 30 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c8cc01096j

Reference yield: 55.0%

2-allylphenol (695-84-1) + acetyl chloride (75-36-5) → 2-acetoxystyrene (63600-35-1)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 2.5h;

DOI:10.1021/jacs.9b02198

upstream raw materials:

acetic anhydride

2-allylphenol

cycloocta-2,4,6-trien-1-one

acetylene

Downstream raw materials:

2-allylphenol

methyl 3-(2-acetoxyphenyl)propanoate

(-)-(2S,3'S,4'R,6'R)-6'-(2-(tert-butyldiphenylsilyloxy)ethyl)-4'-(triisopropylsilyloxy)-3',4',5',6'-tetrahydrospiro[chroman-2,2'-pyran]-3'-ol

(+)-(2R,3'R,4'S,6'R)-6'-(2-(tert-butyldiphenylsilyloxy)ethyl)-4'-(triisopropylsilyloxy)-3',4',5',6'-tetrahydrospiro[chroman-2,2'-pyran]-3'-ol

Refernces

• 1、 Cong, Fei,Wei, Yongliang,Tang, Pingping. "Combining photoredox and silver catalysis for azidotrifluoromethoxylation of styrenes". supporting information. p. 4473 - 4476. Retrieved 2018/05/03.
• 2、 Liu, Guodong,Wurst, Jacqueline M.,Tan, Derek S.. "Stereoselective synthesis of benzannulated spiroketals: Influence of the aromatic ring on reactivity and conformation". supporting information; experimental part. p. 3670 - 3673. Retrieved 2011/03/18.