2-Aminobenzimidazole

Base Information

• Chemical Name: 2-Aminobenzimidazole
• CAS No.: 934-32-7
• Deprecated CAS: 144704-99-4
• Molecular Formula: C7H7N3
• Molecular Weight: 133.153
• Hs Code.: 2933.99
• European Community (EC) Number: 213-280-6
• NSC Number: 27793,7628
• UNII: E65DE7521V
• DSSTox Substance ID: DTXSID1024465
• Nikkaji Number: J3.655B
• Wikidata: Q27103356
• Metabolomics Workbench ID: 51469
• ChEMBL ID: CHEMBL305513
• Mol file: 934-32-7.mol

Synonyms:2-aminobenzimidazole;2-aminobenzimidazole hydrochloride;2-aminobenzimidazole monobenzoate;2-aminobenzimidazole monohydrochloride;2-aminobenzimidazole monoperchlorate;2-aminobenzimidazole monosulfate;2-aminobenzimidazole sulfate;2-aminobenzimidazole sulfate (2:1);2-aminobenzimidazole tartrate(2:1), (L)-(+)-isomer;2-aminobenzimidazole, conjugate monoacid

Chemical Property of 2-Aminobenzimidazole

Chemical Property:

• Appearance/Colour: light yellow to cream or beige powder or flakes
• Vapor Pressure: 1.23E-05mmHg at 25°C
• Melting Point: 226-230 °C(lit.)
• Refractive Index: 1.78
• Boiling Point: 368.9 °C at 760 mmHg
• PKA: 11.41±0.10(Predicted)
• Flash Point: 204.6 °C
• PSA: 54.70000
• Density: 1.367 g/cm³
• LogP: 1.72630
• Storage Temp.: Store below +30°C.
• Solubility.: <1g/l slightly soluble
• Water Solubility.: Soluble in water (Slightly).
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 133.063997236
• Heavy Atom Count: 10
• Complexity: 126

Purity/Quality:

99%min ^*data from raw suppliers

2-Aminobenzimidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38-43
• Safety Statements: 26-36/37/39-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)NC(=N2)N
• Uses: 2-Aminobenzimidazole was used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.

Technology Process of 2-Aminobenzimidazole

There total 50 articles about 2-Aminobenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-azido-1H-benzo[d]imidazole (1516-74-1) → 1H-benzimidazol-2-amine (934-32-7)

Guidance literature:

With sodium tetrahydroborate; tin bis(1,2-benzenethiolate); In tetrahydrofuran; phosphate buffer; at 10 ℃; for 0.5h; pH=10;

DOI:10.1021/ol991359z

Reference yield: 97.0%

bromocyane (506-68-3) + 1,2-diamino-benzene (95-54-5) → 1H-benzimidazol-2-amine (934-32-7)

Guidance literature:

In methanol; water; at 20 - 60 ℃; Inert atmosphere;

Reference yield: 95.0%

aminoiminomethanesulfonic acid (1184-90-3) + 1,2-diamino-benzene (95-54-5) → 1H-benzimidazol-2-amine (934-32-7)

Guidance literature:

In isopropyl alcohol; at 60 ℃;

DOI:10.1002/cjoc.201190179

upstream raw materials:

1H-benzimidazole-2-sulfonic acid

bromocyane

1,2-diamino-benzene

2-azido-1H-benzo[d]imidazole

Downstream raw materials:

2-methylpyrimido[1,2-a]benzimidazol-4(1H)-one

2-Methylpyrimido<1,2-a>benzimidazol

alloxazine

2-phenyl-1H-benz[4,5]imidazo[1,2-a]pyrimidin-4-one

Refernces

• 1、 Panadés, Ricard,Ibarz, Albert,Esplugas, Santiago. "Photodecomposition of carbendazim in aqueous solutions". . p. 2951 - 2954. Retrieved 2000.
• 2、 Abdurazakov,Saidov,Okmanov,Kubaev,Elmuradov, Burkhon Zhurayevich. "Alternative and efficient method for the preparation of 2-acetamidobenzimidazoles". . p. 2247 - 2252. Retrieved 2021/04/22.