N-(7-methoxyquinoxalin-5-yl)acetamide

Base Information

• Chemical Name: N-(7-methoxyquinoxalin-5-yl)acetamide
• CAS No.: 7403-15-8
• Molecular Formula: C₁₁H₁₁N₃O₂
• Molecular Weight: 217.227
• Mol file: 7403-15-8.mol

Synonyms:NSC400392

Chemical Property of N-(7-methoxyquinoxalin-5-yl)acetamide

Chemical Property:

• Vapor Pressure: 1.02E-08mmHg at 25°C
• Boiling Point: 462°Cat760mmHg
• Flash Point: 233.2°C
• Density: 1.3g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(7-methoxyquinoxalin-5-yl)acetamide

There total 5 articles about N-(7-methoxyquinoxalin-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methoxy-benzene-1,2,3-triyltriamine; dihydrochloride → N-(7-methoxy-quinoxalin-5-yl)-acetamide (7403-15-8)

Guidance literature:

Multi-step reaction with 2 steps

1: water; Na₂CO₃

With water; sodium carbonate;

DOI:10.1039/jr9450000791

Reference yield:

7-methoxy-5-nitro-quinoxaline (64457-69-8) → N-(7-methoxy-quinoxalin-5-yl)-acetamide (7403-15-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Na₂S₂O₄; water; ethanol

With sodium dithionite; ethanol; water;

DOI:10.1021/ja01226a009

Reference yield:

4-amino-1-methoxy-3,5-dinitrobenzene (5350-56-1) → N-(7-methoxy-quinoxalin-5-yl)-acetamide (7403-15-8)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogen sulfide; aq.-ethanolic ammonia

2: H₂O

3: Na₂S₂O₄; water; ethanol

With ammonium hydroxide; sodium dithionite; ethanol; hydrogen sulfide; water;

DOI:10.1021/ja01226a009

upstream raw materials:

7-methoxy-quinoxalin-5-ylamine

acetic anhydride

7-methoxy-5-nitro-quinoxaline

4-amino-1-methoxy-3,5-dinitrobenzene