RARECHEM AL BD 0181

Base Information

• Chemical Name: RARECHEM AL BD 0181
• CAS No.: 63826-59-5
• Molecular Formula: C6H8OS
• Molecular Weight: 128.195
• Hs Code.: 2934999090
• Mol file: 63826-59-5.mol

Synonyms:2-thiophenemethanol,5-methyl;(5-methyl-2-thienyl)methanol;(5-methyl-thiophen-2-yl)-methanol;5-Methyl-2-thiophenemethanol;

Chemical Property of RARECHEM AL BD 0181

Chemical Property:

• PSA: 48.47000
• LogP: 1.54880
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

99% ^*data from raw suppliers

(5-Methylthiophen-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of RARECHEM AL BD 0181

There total 2 articles about RARECHEM AL BD 0181 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-hydroxymethyl-5-methylfuran (3857-25-8) → 5-methyl-2-thiophenemethanol (63826-59-5)

Guidance literature:

With perchloric acid; hydrogen sulfide; In ethanol; Ambient temperature; Other acids (trichloroacetic acid, hydrochloric acid or hydrogen chloride).;

Reference yield:

2-Methylthiophene (554-14-3) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 5-methyl-2-thiophenemethanol (63826-59-5) + 5,5'-dimethyldi-2-thienylmethane (4218-22-8)

Guidance literature:

With Amberlyst 15; for 12h; Title compound not separated from byproducts;

DOI:10.1007/BF00515576

Reference yield: 95.0%

5-methyl-2-thiophenemethanol (63826-59-5) + benzoyl chloride (98-88-4) → (5-methyl-2-thiophene-yl)methyl benzoate (157890-50-1)

Guidance literature:

With triethylamine; In diethyl ether; for 20h; Ambient temperature;

DOI:10.1021/jo961528i

upstream raw materials:

2-Methylthiophene

formaldehyd

2-hydroxymethyl-5-methylfuran

Downstream raw materials:

2-(chloromethyl)-5-(methyl)thiophene

5,5'-dimethyldi-2-thienylmethane

C₁₂H₁₄OS₂

(Z)-3-Hexen-1-ol

Refernces

• 1、 Kharchenko, V. G.,Gubina, T. I.,Markushina, I. A.. "A NEW REACTION IN COMPOUNDS OF THE FURAN SERIES". . p. 343 - 347. Retrieved 2007/10/02.