(R)-4-Chloro-1,3-butanediol

Base Information Edit

Chemical Name:(R)-4-Chloro-1,3-butanediol
CAS No.:125605-10-9
Molecular Formula:C4H9ClO2
Molecular Weight:124.567
Hs Code.:
UNII:5LY2WU5NY6
Nikkaji Number:J890.507J
Mol file:125605-10-9.mol

Synonyms:(R)-4-CHLORO-1,3-BUTANEDIOL;125605-10-9;(3R)-4-chlorobutane-1,3-diol;(3R)-4-chloro-1,3-butanediol;5LY2WU5NY6;SCHEMBL4787058;(R)-4-chlorobutane-1,3-diol;IQDXPPKWNPMHJI-SCSAIBSYSA-N;4-Chloro-1,3-butanediol, (3R)-;AKOS006271425;1,3-Butanediol, 4-chloro-, (R)-;1,3-Butanediol, 4-chloro-, (3R)-

Suppliers and Price of (R)-4-Chloro-1,3-butanediol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3R)-4-CHLOROBUTANE-1,3-DIOL 95.00%
5MG
$ 502.14

Total 29 raw suppliers

Chemical Property of (R)-4-Chloro-1,3-butanediol Edit

Chemical Property:

Vapor Pressure:0.000914mmHg at 25°C
Refractive Index:1.473
Boiling Point:270.2 °C at 760 mmHg
PKA:13.61±0.20(Predicted)
Flash Point:117.2 °C
PSA：40.46000
Density:1.229 g/cm³
LogP:-0.03150
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:124.0291072
Heavy Atom Count:7
Complexity:40.7

Purity/Quality:

99%, ^*data from raw suppliers

(3R)-4-CHLOROBUTANE-1,3-DIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CO)C(CCl)O
Isomeric SMILES:C(CO)[C@H](CCl)O
Use Description (R)-4-chloro-1,3-butanediol is a chemical compound with various applications across different fields. In the pharmaceutical industry, it serves as a crucial chiral building block for the synthesis of pharmaceutical compounds, enabling the production of optically pure drugs and intermediates. In the field of agrochemicals, it can be used as a starting material for the development of crop protection agents and pesticides. Additionally, in the realm of organic chemistry, this compound plays a vital role as a chiral auxiliary for asymmetric synthesis, facilitating the creation of complex molecules with precise stereochemistry. Its versatility as a chiral building block and auxiliary highlights its significance in pharmaceuticals, agrochemicals, and organic synthesis, contributing to advancements in drug development and chemical research.

Technology Process of (R)-4-Chloro-1,3-butanediol

There total 3 articles about (R)-4-Chloro-1,3-butanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 10488-69-4,86728-85-0,87068-18-6,90866-33-4
ethyl (L)-4-chloro-3-hydroxybutyrate

: 125605-10-9
(3R)-4-chloro-1,3-butanediol

Guidance literature:: ethyl (L)-4-chloro-3-hydroxybutyrate; With sodium tetrahydroborate; In methanol; toluene; at 20 ℃; for 12h;

With hydrogenchloride; water; In methanol; toluene; at 10 ℃;

Reference yield:

: 86728-85-0,87068-18-6,90866-33-4,10488-69-4
ethyl 4-chloro-3-hydroxybutanoate

: 139013-68-6
(3S)-4-chloro-1,3-butanediol

: 125605-10-9
(3R)-4-chloro-1,3-butanediol

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;
DOI:10.1002/jlac.199719970911