Methylphosphonic acid dipropyl ester

Base Information

• Chemical Name: Methylphosphonic acid dipropyl ester
• CAS No.: 6410-56-6
• Molecular Formula: C7H17O3P
• Molecular Weight: 180.184
• Hs Code.: 2931900090
• Mol file: 6410-56-6.mol

Synonyms:propyl methylphosphonate;Methylphosphonsaeure-di-n-propylester;Methanphosphonsaeure-dipropylester;Methyl-phosphonsaeure-dipropylester;methylphosphonic acid dipropyl ester;di-n-propyl methylphosphonate;

Chemical Property of Methylphosphonic acid dipropyl ester

Chemical Property:

• Vapor Pressure: 0.123mmHg at 25°C
• PSA: 45.34000
• LogP: 2.66250

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methylphosphonic acid dipropyl ester

There total 14 articles about Methylphosphonic acid dipropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methylphosphonic acid dichloroanhydride (676-97-1) + propan-1-ol (71-23-8) → methylphosphonic acid dipropyl ester (6410-56-6)

Guidance literature:

With aluminum oxide; at 20 ℃;

Reference yield: 90.0%

propan-1-ol (71-23-8) + methylphosphonic acid (993-13-5) → methylphosphonic acid dipropyl ester (6410-56-6)

Guidance literature:

With p-TsOH-Celite; at 20 ℃;

DOI:10.3184/030823407X218066

Reference yield: 84.0%

propan-1-ol (71-23-8) + Methylphosphonsaeure-monopropylester (4546-11-6) → methylphosphonic acid dipropyl ester (6410-56-6)

Guidance literature:

With polymer supported sulfonated magnetic resin; In toluene; at 20 - 70 ℃; for 0.75h;

DOI:10.1016/j.tetlet.2014.10.086

upstream raw materials:

tri-n-propyl phosphite

methyl bromide

methyl iodide

propan-1-ol

Refernces

• 1、 Purohit, Ajay Kumar,Kumar, Ajeet,Singh, Varoon,Goud D, Raghavender,Jain, Rajiv,Dubey. "Polymer-supported sulfonated magnetic resin: An efficient reagent for esterification of O-alkyl alkylphosphonic-and carboxylic-acids". supporting information. p. 6844 - 6846. Retrieved 2015/01/09.
• 2、 Gupta, Arvind K.,Kumar, Rajesh,Dubey, Devendra K.,Kaushik. "P-Toluenesulfonic acid-Celite as a reagent for synthesis of esters of alkylphosphonic acids under solvent-free conditions". . p. 328 - 331. Retrieved 2008/02/10.