Phosphorous acid,diethyl ester

Base Information

• Chemical Name: Phosphorous acid,diethyl ester
• CAS No.: 123-22-8
• Molecular Formula: C₄H₁₁O₃P
• Molecular Weight: 138.103
• Mol file: 123-22-8.mol

Synonyms:Diethylphosphorous acid; NSC 5273; NSC 72726

Chemical Property of Phosphorous acid,diethyl ester

Chemical Property:

• Boiling Point: 207°Cat760mmHg
• Flash Point: 79°C
• Density: g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphorous acid,diethyl ester

There total 27 articles about Phosphorous acid,diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

ethanol (64-17-5) → Diethyl phosphonate (762-04-9,123-22-8)

Guidance literature:

With phosphorus trichloride; In chloroform; at 30 ℃; Temperature; Flow reactor;

Reference yield: 87.2%

diethyl chlorophosphate (814-49-3) → Diethyl phosphonate (762-04-9,123-22-8)

Guidance literature:

With sodium tetrahydroborate; In 1,4-dioxane; for 5h; Heating;

Reference yield: 83.0%

diethoxyphosphino ethyl cyclohexylphosphonate (96529-96-3) → Diethyl phosphonate (762-04-9,123-22-8)

Guidance literature:

With water; In benzene; for 0.5h; Heating; argon atmosphere;

upstream raw materials:

2,3-dihydro-2-methylene-1,4-benzodioxin

ethanol

methyl phosphite

triethyl trithiophosphite

Downstream raw materials:

diethyl N-benzylphosphoramidate

2-Mercaptobenzothiazole

diethyl 1-hydroxybutylphosphonate

4-methylbenzoic acid ethyl ester

Refernces

• 1、 Pevzner,Sokolova. "Synthesis and Selected Reactions of 2(3)-Furoyl Phosphonates Functionalyzed at the Neighbor Position of the Furan Ring". . p. 1604 - 1619. Retrieved 2019.
• 2、 Sal'Keeva,Taishibekova,Minaeva,Shibaeva,Kasenov,Sal'Keeva,Muratbekova. "Flame retardant properties of phosphorylated derivatives of malonic ester". . p. 659 - 662. Retrieved 2013.
• 3、 Keglevich, Gyoergy,Balint, Erika,Kangyal, Reka,Balint, Maria,Milen, Matyas. "A critical overview of the kabachnik-fields reactions utilizing trialkyl phosphites in water as the reaction medium: A study of the benzaldehyde- benzylamine triethyl phosphite/diethyl phosphite models". . p. 282 - 289. Retrieved 2014.