Phenethylamine, N,N-dimethyl-, hydrochloride

Base Information

• Chemical Name: Phenethylamine, N,N-dimethyl-, hydrochloride
• CAS No.: 10275-21-5
• Molecular Formula: C10H16ClN
• Molecular Weight: 185.697
• Hs Code.: 2921499090
• NSC Number: 169247
• UNII: 0B645VB20Y
• DSSTox Substance ID: DTXSID20145487
• Wikidata: Q27236565
• Mol file: 10275-21-5.mol

Synonyms:AF 2975;AF-2975;AF2975;dimethylphenethylamine;N,N-dimethyl-2-phenylethylamine;N,N-dimethylphenylethylamine;N,N-dimethylphenylethylamine hydrobromide;N,N-dimethylphenylethylamine hydrochloride;N,N-DMPEA

Chemical Property of Phenethylamine, N,N-dimethyl-, hydrochloride

Chemical Property:

• Melting Point: 200-201.5℃
• Boiling Point: 207.3 °C at 760 mmHg
• Flash Point: 71.4 °C
• PSA: 3.24000
• Density: g/cm³
• LogP: 2.59270
• Storage Temp.: Room Temperature, under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 185.0971272
• Heavy Atom Count: 12
• Complexity: 93

Purity/Quality:

99%min ^*data from raw suppliers

N,N-DimethylbenzeneethanamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC1=CC=CC=C1.Cl
• Description: N,N-Dimethylphenethylamine (hydrochloride) (Item No. 29754) is an analytical reference standard categorized as a phenethylamine. This product is intended for research and forensic applications.
• Uses: N,N-Dimethylbenzeneethanamine is used in the synthesis of squalene synthase inhibitors.

Technology Process of Phenethylamine, N,N-dimethyl-, hydrochloride

There total 2 articles about Phenethylamine, N,N-dimethyl-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

methanol (67-56-1) + 3-phenylpropanoyl azide (83421-80-1) → N,N-Dimethyl-β-phenethylamine Hydrochloride (10275-21-5)

Guidance literature:

methanol; 3-phenylpropanoyl azide; at 100 ℃; for 20h; Inert atmosphere;

With C₅₄H₄₃ClN₃P₂Ru⁽¹⁺⁾*F₆P^(1-); potassium carbonate; at 140 ℃; Inert atmosphere;

DOI:10.1039/d0ob01303j

Reference yield:

→ N,N-Dimethyl-β-phenethylamine Hydrochloride (10275-21-5)

Guidance literature:

upstream raw materials:

methanol

3-phenylpropanoyl azide

Refernces

• 1、 -. "Polycyclic amines and intermediates therefor". . . Retrieved 2008/06/13.