2-Aminophenol hydrochloride

Base Information

• Chemical Name: 2-Aminophenol hydrochloride
• CAS No.: 51-19-4
• Molecular Formula: C6H7 N O . Cl H
• Molecular Weight: 145.589
• Hs Code.: 2922299090
• European Community (EC) Number: 621-209-9
• NSC Number: 165648
• DSSTox Substance ID: DTXSID4073122
• Mol file: 51-19-4.mol

Synonyms:2-AMINOPHENOL HYDROCHLORIDE;51-19-4;o-Aminophenol hydrochloride;Phenol, 2-amino-, hydrochloride;2-aminophenol;hydrochloride;o-Hydroxyaniline hydrochloride;Phenol, o-amino-, hydrochloride;NSC 165648;Nc1ccccc1O;2-aminophenol HCl salt;2-Aminophenyl hydrochloride;SCHEMBL387174;DTXSID4073122;O-AMINOPHENYL HYDROCHLORIDE;Aminophenol (ortho-), hydrochloride;MFCD00035471;NSC165648;AKOS016009452;NSC-165648;LS-103918;A0391;FT-0631223;D88256

Chemical Property of 2-Aminophenol hydrochloride

Chemical Property:

• Vapor Pressure: 0.0345mmHg at 25°C
• Melting Point: 207 °C
• Refractive Index: 1.637
• Boiling Point: 234.5 °C at 760 mmHg
• Flash Point: 95.6 °C
• PSA: 46.25000
• Density: 1.21 g/cm³
• LogP: 2.35760
• Storage Temp.: 0-10°C
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 145.0294416
• Heavy Atom Count: 9
• Complexity: 74.9

Purity/Quality:

98%min ^*data from raw suppliers

2-Aminophenol Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N)O.Cl

Technology Process of 2-Aminophenol hydrochloride

There total 6 articles about 2-Aminophenol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-amino-phenol (95-55-6) → 2-aminophenol hydrochloride (51-19-4)

Guidance literature:

With hydrogenchloride; In methanol; for 15h; Inert atmosphere;

Reference yield:

C18H29B2NO5 → 2-aminophenol hydrochloride (51-19-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; acetonitrile; at 20 ℃; for 1h;

DOI:10.1002/adsc.202101043

Reference yield:

3-carboxyethylbenzoxazinone (247571-62-6) → α-ketoglutaric acid (328-50-7) + 2-aminophenol hydrochloride (51-19-4)

Guidance literature:

With hydrogenchloride; In ethanol; for 0.25h; boiling water bath;

upstream raw materials:

3-methyl-1,4-benzoxazin-2-one

ethanol

3-carboxyethylbenzoxazinone

3-phenyl-1,4-benzoxazin-2-one

Downstream raw materials:

2,3-dimethyl-quinolin-8-ol

N-(2-hydroxyphenyl)-N'-phenylthiourea

phenoxazine

N-(2-hydroxyphenyl)benzenesulfonamide

Refernces

• 1、 -. "METHOD FOR SYNTHESIZING RAMALIN AND RAMALIN PRECURSOR BY USING GLUTAMIC ACID DERIVATIVE AND HYDROXY ANILINE OR HYDROXY ANILINE HAVING PROTECTED HYDROXY GROUP". Paragraph 0032; 0033; 0034; 0035; 0036; 0037. . Retrieved 2015/01/18.
• 2、 -. " METHOD FOR PREPARING RAMALIN ". Paragraph 0056. . Retrieved 2013/08/28.