1,3-diphenylprop-2-ynylbenzene

Base Information

• Chemical Name: 1,3-diphenylprop-2-ynylbenzene
• CAS No.: 5467-43-6
• Molecular Formula: C21H16
• Molecular Weight: 268.358
• Mol file: 5467-43-6.mol

Synonyms:

Chemical Property of 1,3-diphenylprop-2-ynylbenzene

Chemical Property:

• Boiling Point: 421.8°Cat760mmHg
• Flash Point: 204.4°C
• Density: 1.1g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-diphenylprop-2-ynylbenzene

There total 38 articles about 1,3-diphenylprop-2-ynylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,1-Diphenylmethanol (91-01-0) + phenylacetylene (536-74-3) → 1,3,3-triphenylpropyne (5467-43-6)

Guidance literature:

With 4-n-butyl-4-(3-sulfopropyl)thiomorpholinium 1,1-dioxide trifluoromethane sulfonate; at 100 ℃; for 2h; Reagent/catalyst; Green chemistry;

DOI:10.1002/cssc.201402220

Reference yield: 95.0%

1,1-Diphenylmethanol (91-01-0) + 1-Phenyl-2-(trimethylsilyl)acetylene (2170-06-1) → 1,3,3-triphenylpropyne (5467-43-6)

Guidance literature:

bismuth(III) chloride; In dichloromethane; Heating;

DOI:10.1016/j.tetlet.2005.09.161

Reference yield: 89.0%

N-tosyl-N-benzyl-1,1-diphenylmethylamine + phenylacetylene (536-74-3) → 1,3,3-triphenylpropyne (5467-43-6)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; bis(trifluoromethanesulfonyl)amide; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; at 90 ℃; for 24h; Inert atmosphere;

DOI:10.1002/cjoc.201400194

upstream raw materials:

phenylethynylmagnesium bromide

diphenylchloromethane

methanol

1,1,3-triphenylpropa-1,2-diene

Downstream raw materials:

(Z)-1-methoxy-1,3,3-triphenylpropene

(E)-1-methoxy-1,3,3-triphenylpropene

1,1,3-triphenyl-buta-1,2-diene

1,2,2-triphenylethan-1-one

Refernces

• 1、 Dasgupta, Ayan,Stefkova, Katarina,Babaahmadi, Rasool,Yates, Brian F.,Buurma, Niklaas J.,Ariafard, Alireza,Richards, Emma,Melen, Rebecca L.. "Site-Selective Csp3-Csp/Csp3-Csp2Cross-Coupling Reactions Using Frustrated Lewis Pairs". supporting information. p. 4451 - 4464. Retrieved 2021/04/07.
• 2、 Nayal, Onkar S.,Thakur, Maheshwar S.,Kumar, Manoranjan,Kumar, Neeraj,Maurya, Sushil K.. "Ligand-free Iron(II)-Catalyzed N-Alkylation of Hindered Secondary Arylamines with Non-activated Secondary and Primary Alcohols via a Carbocationic Pathway". supporting information. p. 730 - 737. Retrieved 2017/12/26.