1,2,4,5-Benzenetetracarboxylic acid, 1,5-dimethyl ester

Base Information

• Chemical Name: 1,2,4,5-Benzenetetracarboxylic acid, 1,5-dimethyl ester
• CAS No.: 28132-03-8
• Molecular Formula: C12H10O8
• Molecular Weight: 282.207
• DSSTox Substance ID: DTXSID60885411
• Nikkaji Number: J695.793E
• Wikidata: Q82864034
• Mol file: 28132-03-8.mol

Synonyms:28132-03-8;1,2,4,5-Benzenetetracarboxylic acid, 1,5-dimethyl ester;dimethyl dihydrogen pyromellitate;DTXSID60885411;1,2,4,5-Benzenetetracarboxylic acid 1,5-dimethyl ester

Chemical Property of 1,2,4,5-Benzenetetracarboxylic acid, 1,5-dimethyl ester

Chemical Property:

• Vapor Pressure: 8.88E-12mmHg at 25°C
• Boiling Point: 523.3°Cat760mmHg
• Flash Point: 203.6°C
• Density: 1.483g/cm³
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 282.03756727
• Heavy Atom Count: 20
• Complexity: 391

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC(=C(C=C1C(=O)O)C(=O)O)C(=O)OC

Technology Process of 1,2,4,5-Benzenetetracarboxylic acid, 1,5-dimethyl ester

There total 3 articles about 1,2,4,5-Benzenetetracarboxylic acid, 1,5-dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.2%

1,5-dibenzyl 2,4-dimethyl benzene-1,2,4,5-tetracarboxylate (1036648-88-0) → 1,3-dicarbomethoxy 4,6-benzenedicarboxylic acid (28132-03-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 20 ℃; under 760.051 Torr;

DOI:10.1021/jo800543w

Reference yield: 26.0%

methanol (67-56-1) + Pyromellitic dianhydride (89-32-7,34527-94-1) → 1,3-dicarbomethoxy 4,6-benzenedicarboxylic acid (28132-03-8)

Guidance literature:

With magnesium; at 60 ℃; for 2h;

DOI:10.1007/s10870-007-9262-1

Reference yield:

→ 1,3-dicarbomethoxy 4,6-benzenedicarboxylic acid (28132-03-8)

Guidance literature:

Pyromellitsaeure-dianhydrid, Me., Rueckfluss;

upstream raw materials:

methanol

Pyromellitic dianhydride

1,5-dibenzyl 2,4-dimethyl benzene-1,2,4,5-tetracarboxylate

Refernces

• 1、 Paine III, John B.. "Esters of pyromellitic acid. Part I. Esters of achiral alcohols: Regioselective synthesis of partial and mixed pyromellitate esters, mechanism of transesterification in the quantitative esterification of the pyromellitate system using orthoformate esters, and a facile synthesis of the ortho pyromellitate diester substitution pattern". . p. 4929 - 4939. Retrieved 2008/12/21.