(R,S)-1-Tosyl Glycerol

Base Information

• Chemical Name: (R,S)-1-Tosyl Glycerol
• CAS No.: 6047-51-4
• Molecular Formula: C₁₆H₂₁NO
• Molecular Weight: 243.349
• DSSTox Substance ID: DTXSID60975881
• Nikkaji Number: J32.716F
• Mol file: 6047-51-4.mol

Synonyms:(R,S)-1-Tosyl Glycerol;73073-07-1;2,3-dihydroxypropyl 4-methylbenzenesulfonate;6047-51-4;1-Tosyloxy-2,3-propanediol;2,3-Dihydroxypropyl Tosylate;1-O-tosyl-glycerol;(R,S)-1-TosylGlycerol;glycerol p-toluenesulfonate;SCHEMBL2548351;DTXSID60975881;DFQNMODTAFTGHS-UHFFFAOYSA-N;(+/-)-2,3-Dihydroxypropyl tosylate;AKOS030255502;FT-0605134;FT-0605306;FT-0675325;FT-0675326;2,3-Dihydroxypropyl 4-methylbenzene-1-sulfonate;3-[(4-methylbenzenesulfonyl)oxy]propane-1,2-diol

Chemical Property of (R,S)-1-Tosyl Glycerol

Chemical Property:

• Vapor Pressure: 2.27E-09mmHg at 25°C
• Boiling Point: 463°Cat760mmHg
• Flash Point: 233.8°C
• Density: 1.351g/cm³
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 246.05619472
• Heavy Atom Count: 16
• Complexity: 287

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC(CO)O

Technology Process of (R,S)-1-Tosyl Glycerol

There total 4 articles about (R,S)-1-Tosyl Glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Bromo-2'-acetonaphthone (613-54-7) → 2-butylamino-1-[2]naphthyl-ethanol (6047-51-4)

Guidance literature:

Multi-step reaction with 2 steps

1: DMSO

2: NaBH₄

With sodium tetrahydroborate; dimethyl sulfoxide;

DOI:10.1021/jm00311a020

Reference yield:

2-naphthylglyoxal (22115-06-6) + N-butylamine (109-73-9,85404-21-3) → 2-butylamino-1-[2]naphthyl-ethanol (6047-51-4)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1021/jm00311a020

Reference yield:

→ 2-butylamino-1-[2]naphthyl-ethanol (6047-51-4)

Guidance literature:

With ethanol; palladium; Hydrogenation;

DOI:10.1021/jo01211a005

upstream raw materials:

2-naphthylglyoxal

N-butylamine

2-Bromo-2'-acetonaphthone

Refernces