2-iodobenzene-1,3-dicarboxylic acid

Base Information

• Chemical Name: 2-iodobenzene-1,3-dicarboxylic acid
• CAS No.: 2902-65-0
• Molecular Formula: C8H5 I O4
• Molecular Weight: 292.03
• Mol file: 2902-65-0.mol

Synonyms:Isophthalicacid, 2-iodo- (7CI,8CI); 2-Iodo-1,3-benzenedicarboxylic acid; 2-Iodoisophthalicacid; NSC 266280

Chemical Property of 2-iodobenzene-1,3-dicarboxylic acid

Chemical Property:

• Vapor Pressure: 3.29E-08mmHg at 25°C
• Melting Point: 243.0 to 246.0 °C
• Boiling Point: 431.4°Cat760mmHg
• PKA: 2.19±0.10(Predicted)
• Flash Point: 214.7°C
• PSA: 74.60000
• Density: 2.138g/cm³
• LogP: 1.68760
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Iodoisophthalic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-iodobenzene-1,3-dicarboxylic acid

There total 7 articles about 2-iodobenzene-1,3-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-aminoisophthalic acid (39622-79-2) → 2-iodoyl-1,3-benzenedicarboxylic acid (2902-65-0)

Guidance literature:

With sulfuric acid; potassium iodide; sodium nitrite; In water;

DOI:10.1016/j.tet.2020.131634

Reference yield: 52.0%

2,6-dimethyliodobenzene (608-28-6) → 2-iodoyl-1,3-benzenedicarboxylic acid (2902-65-0)

Guidance literature:

With potassium permanganate; In water; tert-butyl alcohol; at 90 ℃; for 18h;

DOI:10.1002/anie.201910352

Reference yield:

→ 2-iodoyl-1,3-benzenedicarboxylic acid (2902-65-0)

Guidance literature:

With iodine; potassium iodide;

DOI:10.1021/ja01386a024

upstream raw materials:

2,6-dimethyliodobenzene

2-aminoisophthalic acid

2,6-dimethylaniline

3-methyl-2-nitrobenzoic acid

Downstream raw materials:

Dimethyl 2-iodoisophthalate

2-(2-carboxyphenylamino)benzene-1,3-dioic acid

2-(2-Chloro-phenylamino)-isophthalic acid

N-(2.3-Xylyl)2-aminoisophthalsaeure

Refernces

• 1、 Tariq, M.Umair,Moran, Wesley J.. "Design and synthesis of chiral urea-derived iodoarenes and their assessment in the enantioselective dearomatizing cyclization of a naphthyl amide". . . Retrieved 2020/10/12.
• 2、 Shelly, Kevin P.,Venimadhavan, S.,Nagarajan, K.,Stewart, Ross. "General acid catalysis in the enolization of acetone". . p. 1274 - 1282. Retrieved 2007/10/02.