Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine

Base Information Edit

Chemical Name:Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine
CAS No.:5981-17-9
Molecular Formula:C₁₂H₂₁N₃
Molecular Weight:207.319
Hs Code.:
DSSTox Substance ID:DTXSID40208548
Nikkaji Number:J730.099I
Wikidata:Q83082661
Mol file:5981-17-9.mol

Synonyms:5981-17-9;Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine;1,6,11-triazatetracyclo[10.3.0.02,6.07,11]pentadecane;Dodecahydro-Tripyrrolo[1,2-a:1',2'-c:1'',2''-e][1,3,5]triazine;tripyrroline;SCHEMBL7944978;DTXSID40208548;A18958;Dodecahydrotripyrrolo[1,2-a:1',2'-c:1",2"-e][1,3,5]triazine;Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'''',2''''-e)(1,3,5)triazine;Tripyrrolo[1,2-a:1',2'-c:1'',2''-e][1,3,5]triazine, dodecahydro-

Suppliers and Price of Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Tripyrroline
25mg
$ 1680.00

Total 6 raw suppliers

Chemical Property of Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine Edit

Chemical Property:

Boiling Point:311.1°Cat760mmHg
PKA:6.61±0.20(Predicted)
Flash Point:161.2°C
PSA：9.72000
Density:1.19g/cm³
LogP:1.07940
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:207.173547683
Heavy Atom Count:15
Complexity:219

Purity/Quality:

98%Min ^*data from raw suppliers

Tripyrroline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2N(C1)C3CCCN3C4N2CCC4
Uses Tripyrroline is used as a reagent in the synthesis of potent and selective phosphinic peptide inhibitors of angiotensin-converting enzyme 2. Tripyrroline is also used in the total synthesis of Febrifugine (F228500, 2HCl); a bioactive constituent of a Chinese medicinal herb that is characterized by its therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.

Technology Process of Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine

There total 4 articles about Dodecahydrotripyrrolo(1,2-a:1',2'-c:1'',2''-e)(1,3,5)triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.7%

: 7223-42-9
1-(prop-2-yn-1-yl)pyrrolidine

: 13618-87-6
1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole

: 463-49-0
1,2-propanediene

: 51463-41-3,851390-85-7
2,3,5,7a-tetrahydro-1H-pyrrolizine

: 5981-17-9,64314-29-0
dodecahydro-3a,6a,9a-triaza-trindene

Guidance literature:: at 450 ℃; under 12 Torr; Product distribution; Mechanism; other temperature and pressure;
DOI:10.1021/jo00071a015

Reference yield:

: 123-75-1
pyrrolidine

: 5724-81-2
1-pyrroline

: 5981-17-9,64314-29-0
dodecahydro-3a,6a,9a-triaza-trindene

Guidance literature:: With binuclear copper(II) complex of 1H-pyrrolo<2,3-b>pyridine; oxygen; In N,N-dimethyl-formamide; for 20h; under 760 Torr; Title compound not separated from byproducts; Ambient temperature;
DOI:10.1246/cl.1997.311

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 5724-81-2
1-pyrroline

: 5981-17-9,64314-29-0
(3bR,6bR,9bR)-Dodecahydro-3a,6a,9a-triaza-trindene

Guidance literature:: With iodosylbenzene; In dichloromethane-d2; for 24h; Yield given. Yields of byproduct given; Ambient temperature;
DOI:10.1016/S0040-4039(00)88474-9