6-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE

Base Information

• Chemical Name: 6-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE
• CAS No.: 159954-28-6
• Molecular Formula: C₁₄H₁₆ClNO₆
• Molecular Weight: 329.737
• Hs Code.: 29400090
• Mol file: 159954-28-6.mol

Synonyms:6-Chloro-3-indolyl |?-D-glucopyranoside;

Chemical Property of 6-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE

Chemical Property:

• Appearance/Colour: white to off-white powder
• Vapor Pressure: 9.45E-17mmHg at 25°C
• Refractive Index: 1.717
• Boiling Point: 630.228 °C at 760 mmHg
• PKA: 12.84±0.70(Predicted)
• Flash Point: 334.95 °C
• PSA: 115.17000
• Density: 1.641 g/cm³
• LogP: -0.00000
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

6-Chloro-3-indolyl b-D-glucopyranoside ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 6-Chloro-3-indolyl β-D-Glucopyranoside is a substrate used as a chromogenic medium for the detection of yeasts with β-glucosidase activity.

Technology Process of 6-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE

There total 4 articles about 6-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

C24H26ClNO11 → 6-chloro-3-indol-α-D-glucopyranoside (467214-46-6,159954-28-6,198402-61-8,425427-88-9,796842-57-4)

Guidance literature:

With sodium methylate; In methanol;

Reference yield:

α-D-glucopyranose peracetylate (604-68-2) → 6-chloro-3-indol-α-D-glucopyranoside (467214-46-6,159954-28-6,198402-61-8,425427-88-9,796842-57-4)

Guidance literature:

Multi-step reaction with 4 steps

1: acetonitrile / 12 h / 20 °C

2: potassium carbonate / dichloromethane / 6 h / 20 °C / Inert atmosphere

3: boron trifluoride diethyl etherate / dichloromethane / 9 h / 20 °C / Inert atmosphere

4: sodium methylate / methanol

With boron trifluoride diethyl etherate; sodium methylate; potassium carbonate; In methanol; dichloromethane; acetonitrile;

Reference yield:

2,3,4,6-tetraacetylglucose (3947-62-4,10343-06-3,19235-21-3,22554-70-7,22860-22-6,47339-09-3,57884-82-9,62057-79-8,70191-05-8,109525-54-4,140147-37-1,6207-76-7) → 6-chloro-3-indol-α-D-glucopyranoside (467214-46-6,159954-28-6,198402-61-8,425427-88-9,796842-57-4)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / dichloromethane / 6 h / 20 °C / Inert atmosphere

2: boron trifluoride diethyl etherate / dichloromethane / 9 h / 20 °C / Inert atmosphere

3: sodium methylate / methanol

With boron trifluoride diethyl etherate; sodium methylate; potassium carbonate; In methanol; dichloromethane;

upstream raw materials:

α-D-glucopyranose peracetylate

2,3,4,6-tetraacetylglucose

O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate

Refernces