Heptafluoropropyl pentafluoroethyl ether

Base Information

• Chemical Name: Heptafluoropropyl pentafluoroethyl ether
• CAS No.: 66840-50-4
• Deprecated CAS: 113263-98-2,143440-95-3,159095-03-1,39289-55-9,55600-49-2,65863-23-2,66771-81-1,74434-37-0,74434-38-1,80449-91-8,2409008-16-6
• Molecular Formula: C5F12O
• Molecular Weight: 304.035
• Hs Code.: 2909199090
• European Community (EC) Number: 611-940-1
• DSSTox Substance ID: DTXSID80892066
• Wikidata: Q81981962
• Mol file: 66840-50-4.mol

Synonyms:60164-51-4;Heptafluoropropyl pentafluoroethyl ether;66840-50-4;1-(Perfluoroethoxy)perfluoropropane;1,1,1,2,2,3,3-heptafluoro-3-(pentafluoroethoxy)propane;1,1,1,2,2,3,3-heptafluoro-3-(1,1,2,2,2-pentafluoroethoxy)propane;Propane, 1,1,1,2,2,3,3-heptafluoro-3-(pentafluoroethoxy)-;SCHEMBL1594229;DTXSID80892066;YBVRDNKKIWCSHJ-UHFFFAOYSA-N;MFCD09998168;AKOS037621657

Chemical Property of Heptafluoropropyl pentafluoroethyl ether

Chemical Property:

• PSA: 9.23000
• LogP: 3.94850
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 3
• Exact Mass: 303.9757526
• Heavy Atom Count: 18
• Complexity: 297

Purity/Quality:

99% ^*data from raw suppliers

HEPTAFLUOROPROPYL PENTAFLUOROETHYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> Polymers
• Canonical SMILES: C(C(OC(C(F)(F)F)(F)F)(F)F)(C(F)(F)F)(F)F

Technology Process of Heptafluoropropyl pentafluoroethyl ether

There total 8 articles about Heptafluoropropyl pentafluoroethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

cis-2,6-dimethylmorpholine (141-91-3,6485-45-6,6485-55-8) → 2,3,3,4,5,5,6-Heptafluoro-2,6-bis-trifluoromethyl-morpholine (131968-14-4) + 1-ethoxy-perfluoropropane (66840-50-4) + bis(perfluoroisopropyl) ether (83935-39-1) + N,N-Difluoroamino-perfluoro-(2,4-dimethyl-3-oxapentane)

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 8.55h; Yield given. Further byproducts given; electrolysis: 2.7 A/dm², 6.1-6.3 V, 226 A h;

DOI:10.1016/S0022-1139(97)00145-0

Reference yield: 11.8%

methyl [(2R,6S)-2,6-dimethyl-4-morpholinyl]acetate (205876-55-7) → 1-ethoxy-perfluoropropane (66840-50-4) + bis(perfluoroisopropyl) ether (83935-39-1) + Difluoro-((2S,6R)-2,3,3,5,5,6-hexafluoro-2,6-bis-trifluoromethyl-morpholin-4-yl)-acetyl fluoride + Difluoro-((2R,6R)-2,3,3,5,5,6-hexafluoro-2,6-bis-trifluoromethyl-morpholin-4-yl)-acetyl fluoride

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 8.03333h; Further byproducts given. Yields of byproduct given; electrolysis: 3.0 A/dm², 5.9-6.1 V, 220 A h;

DOI:10.1016/S0022-1139(97)00145-0

Reference yield: 3.3%

3-((2R,6S)-2,6-Dimethyl-morpholin-4-yl)-2-methyl-propionic acid methyl ester (205876-57-9) → 1-ethoxy-perfluoropropane (66840-50-4) + (2R,6S)-2,3,3,5,5,6-Hexafluoro-4-heptafluoropropyl-2,6-bis-trifluoromethyl-morpholine + 2,3,3-Trifluoro-3-((2R,6S)-2,3,3,5,5,6-hexafluoro-2,6-bis-trifluoromethyl-morpholin-4-yl)-2-trifluoromethyl-propionyl fluoride + 2,3,3-Trifluoro-3-((2S,6S)-2,3,3,5,5,6-hexafluoro-2,6-bis-trifluoromethyl-morpholin-4-yl)-2-trifluoromethyl-propionyl fluoride

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 10.05h; Further byproducts given. Yields of byproduct given; electrolysis: 3.0 A/dm², 6.2-6.4 V, 208 A h;

DOI:10.1016/S0022-1139(97)00145-0

upstream raw materials:

perfluoro(2-propoxypropionyl) fluoride

methyl [(2R,6S)-2,6-dimethyl-4-morpholinyl]acetate

3-((2R,6S)-2,6-Dimethyl-morpholin-4-yl)-propionic acid methyl ester

3-((2R,6S)-2,6-Dimethyl-morpholin-4-yl)-2-methyl-propionic acid methyl ester

Refernces

• 1、 Moldavskii, Dmitrii D.,Bispen, Tatjana A.,Kaurova, Galina I.,Furin, Georgii G.. "Technology for the preparation of perfluoro-organic compounds". . p. 157 - 167. Retrieved 2007/10/03.
• 2、 Zakharov, V. Yu.,Denisov, A. K.,Novikova, M. D.. "DIRECT GAS-PHASE CATALYTIC FLUORINATION OF PARTIALLY FLUORINATED ORGANIC COMPOUNDS". . p. 1942 - 1945. Retrieved 2007/10/03.