Cyclopentaneacetic acid, 5-(bromoacetyl)-1,3-phenylene ester

Base Information

• Chemical Name: Cyclopentaneacetic acid, 5-(bromoacetyl)-1,3-phenylene ester
• CAS No.: 67656-51-3
• Molecular Formula: C₂₂H₂₇BrO₅
• Molecular Weight: 451.357
• Mol file: 67656-51-3.mol

Synonyms:

Chemical Property of Cyclopentaneacetic acid, 5-(bromoacetyl)-1,3-phenylene ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Cyclopentaneacetic acid, 5-(bromoacetyl)-1,3-phenylene ester

There total 1 articles about Cyclopentaneacetic acid, 5-(bromoacetyl)-1,3-phenylene ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-cyclopentylacetyl chloride (1122-99-2) + 3,5-dihydroxyacetophenone (51863-60-6) → Cyclopentyl-acetic acid 3-(2-bromo-acetyl)-5-(2-cyclopentyl-acetoxy)-phenyl ester (67656-51-3)

Guidance literature:

Multistep reaction; (i) Et₃N, CHCl₃, (ii) Br₂, AlCl₃, AcOtBu;

Reference yield:

N-[2-(benzylamino)ethyl]-2-phenylacetamide (67630-56-2) + Cyclopentyl-acetic acid 3-(2-bromo-acetyl)-5-(2-cyclopentyl-acetoxy)-phenyl ester (67656-51-3) → Cyclopentyl-acetic acid 3-{2-[benzyl-(2-phenylacetylamino-ethyl)-amino]-acetyl}-5-(2-cyclopentyl-acetoxy)-phenyl ester

Guidance literature:

In 1,4-dioxane;

upstream raw materials:

2-cyclopentylacetyl chloride

3,5-dihydroxyacetophenone