1-broMo-4-ethylnaphthalene

Base Information

• Chemical Name: 1-broMo-4-ethylnaphthalene
• CAS No.: 67668-17-1
• Molecular Formula: C12H11Br
• Molecular Weight: 235.123
• Mol file: 67668-17-1.mol

Synonyms:1-Aethyl-4-brom-naphthalin;1-Ethyl-4-bromnaphthalin;

Chemical Property of 1-broMo-4-ethylnaphthalene

Chemical Property:

• PSA: 0.00000
• LogP: 4.16470

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-broMo-4-ethylnaphthalene

There total 2 articles about 1-broMo-4-ethylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-ethylnapthelene (1127-76-0) → 1-bromo-4-ethylnaphthalene (67668-17-1)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1021/acs.orglett.2c00415

Reference yield:

→ 1-bromo-4-ethylnaphthalene (67668-17-1)

Guidance literature:

With water; bromine; sodium bromide;

DOI:10.1021/ja01167a017

Reference yield:

1-bromo-4-ethylnaphthalene (67668-17-1) → 4-ethyl-1-naphthalenecarboxylic acid (91902-58-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CuCN

With CuCN;

DOI:10.1021/ja01167a017

upstream raw materials:

1-ethylnapthelene

Downstream raw materials:

4-ethyl-1-naphthalenecarboxylic acid

(4-ethylnaphthalen-1-yl)boronic acid

Refernces

• 1、 Komatsuda, Masaaki,Muto, Kei,Yamaguchi, Junichiro,Yanagimoto, Aika. "Dearomative Allylation of Naphthyl Cyanohydrins by Palladium Catalysis: Catalyst-Enhanced Site Selectivity". supporting information. p. 3423 - 3427. Retrieved 2020/04/20.