Triphenyl(propyl)phosphonium bromide

Base Information

• Chemical Name: Triphenyl(propyl)phosphonium bromide
• CAS No.: 6228-47-3
• Molecular Formula: C21H22BrP
• Molecular Weight: 385.283
• Hs Code.: 29319090
• European Community (EC) Number: 240-056-5,228-330-2
• NSC Number: 50539
• DSSTox Substance ID: DTXSID80977847
• ChEMBL ID: CHEMBL3334701
• Mol file: 6228-47-3.mol

Synonyms:6228-47-3;Propyltriphenylphosphonium bromide;Triphenyl(propyl)phosphonium bromide;n-Propyltriphenylphosphonium bromide;Triphenylpropylphosphonium bromide;15912-75-1;(1-Propyl)triphenylphosphonium bromide;triphenyl(propyl)phosphanium bromide;triphenyl(propyl)phosphanium;bromide;Phosphonium, triphenylpropyl-, bromide;n-propyl triphenylphosphonium bromide;triphenyl propyl phosphonium bromide;EINECS 228-330-2;MFCD00011843;Propyl triphenyl phosphonium bromide;C21H22P.Br;SCHEMBL164032;C21-H22-P.Br;propyl triphenylphosphine bromide;CHEMBL3334701;DTXSID80977847;propyl triphenylphosphonium bromide;propyl-triphenylphosphonium bromide;propyltriphenyl phosphonium bromide;AMY39384;BCP22569;NSC50539;bromo-tri(phenyl)-propyl-phosphorane;n-propyltriphenyl-phosphonium bromide;NSC 50539;NSC-50539;(n-propyl)triphenylphosphonium bromide;AKOS004908938;CS-W009394;GC10170;AS-14335;SY015709;FT-0605017;P1200;F10028;EN300-6729414;A810001;A833694;W-105021;triphenyl(propyl)phosphonium chloride;Propyltriphenylphosphonium Bromide;(1-PROPYL)TRIPHENYLPHOSPHONIUM BROMIDE;N-PROPYLTRIPHENYLPHOSPHONIUM BROMIDE;PROPYLTRIPHENYLPHOSPHONIUM BROMIDE;TRIPHENYL-N-PROPYLPHOSPHONIUM BROMIDE;TRIPHENYLPROPYLPHOSPHONIUM BROMIDE

Chemical Property of Triphenyl(propyl)phosphonium bromide

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Melting Point: 236-238 °C
• PSA: 13.59000
• LogP: 1.39450
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Sensitive.: Hygroscopic
• Solubility.: DMSO (Sparingly, Heated), Methanol (Slightly)
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 384.06425
• Heavy Atom Count: 23
• Complexity: 260

Purity/Quality:

99% ^*data from raw suppliers

n-PropyltriphenylphosphoniumBromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xn
• Statements: 36/37/38-21/22
• Safety Statements: 36/37-36/37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]
• Uses: n-Propyltriphenylphosphonium Bromide, is an analogue of phosphonium, acting as reversible inhibitors of cholinesterases of different animals. It has also been shown to be part of Phosphonium salts, having antiviral activity against influenza virus A. suzuki reaction

Technology Process of Triphenyl(propyl)phosphonium bromide

There total 4 articles about Triphenyl(propyl)phosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

propyl bromide (106-94-5) + triphenylphosphine (603-35-0) → n-propyltriphenylphosphonium bromide (6228-47-3)

Guidance literature:

for 2h; Heating;

Reference yield: 96.0%

propan-1-ol (71-23-8) + triphenylphosphine (603-35-0) → n-propyltriphenylphosphonium bromide (6228-47-3)

Guidance literature:

With hydrogen bromide; at 110 ℃; for 48h;

Reference yield:

propoxybenzene (622-85-5) + triphenylphosphine hydrobromide (6399-81-1) → n-propyltriphenylphosphonium bromide (6228-47-3)

Guidance literature:

at 160 - 170 ℃;

upstream raw materials:

propoxybenzene

triphenylphosphine hydrobromide

propyl bromide

triphenylphosphine

Downstream raw materials:

(Z)-2-(1-Butenyl)-mesitylen

(E)-1-mesitylbut-1-ene

heptene-4 ol-1

(Z)-9-Dodecensaeure-aethylester

Refernces

• 1、 Strauss, Marcel A.,Wegner, Hermann A.. "Exploring London Dispersion and Solvent Interactions at Alkyl–Alkyl Interfaces Using Azobenzene Switches". supporting information. p. 18552 - 18556. Retrieved 2019/11/19.
• 2、 Kaneko, Ikki,Hoshino, Tsutomu. "β-Amyrin Biosynthesis: Promiscuity for Steric Bulk at Position 23 in the Oxidosqualene Substrate and the Significance of Hydrophobic Interaction between the Methyl Group at Position 30 and the Binding Site". . p. 6657 - 6671. Retrieved 2016/08/16.