Cyclobutanone, 2-chloro-3,3-dimethyl-2-(2,2,2-trichloroethyl)-

Base Information

• Chemical Name: Cyclobutanone, 2-chloro-3,3-dimethyl-2-(2,2,2-trichloroethyl)-
• CAS No.: 68697-08-5
• Molecular Formula: C₈H₁₀Cl₄O
• Molecular Weight: 263.979
• Mol file: 68697-08-5.mol

Synonyms:

Chemical Property of Cyclobutanone, 2-chloro-3,3-dimethyl-2-(2,2,2-trichloroethyl)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclobutanone, 2-chloro-3,3-dimethyl-2-(2,2,2-trichloroethyl)-

There total 5 articles about Cyclobutanone, 2-chloro-3,3-dimethyl-2-(2,2,2-trichloroethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2,2,4,4,4-Pentachlorbuttersaeurechlorid (72060-97-0) + isobutene (115-11-7,15220-85-6) → 2-chloro-2-(2',2',2'-trichloroethyl)-3,3-dimethylcyclobutan-1-one (68697-08-5,117745-42-3,117745-46-7)

Guidance literature:

With ammonium chloride; potassium iodide; zinc; In various solvent(s); at 30 ℃; for 4.5h;

DOI:10.1002/hlca.19810640109

Reference yield: 33.0%

2,4,4,4-Tetrachlorbuttersaeure-1,2,4,4,4-pentachlorbut-1-enylester + isobutene (115-11-7,15220-85-6) → 2-chloro-2-(2',2',2'-trichloroethyl)-3,3-dimethylcyclobutan-1-one (68697-08-5,117745-42-3,117745-46-7)

Guidance literature:

With triethylamine; In cyclohexane; at 25 - 30 ℃; for 3h;

DOI:10.1002/hlca.19810640109

Reference yield: 4.5%

2,4,4,4-tetrachlorobutyric acid chloride (68121-36-8) + isobutene (115-11-7,15220-85-6) → 2-chloro-2-(2',2',2'-trichloroethyl)-3,3-dimethylcyclobutan-1-one (68697-08-5,117745-42-3,117745-46-7) + cis-2-Chlor-4-(2',2',2'-trichloraethyl)-3,3-dimethylcyclobutanon

Guidance literature:

With triethylamine; In cyclohexane; at 65 ℃; for 3h;

DOI:10.1002/hlca.19810640109

upstream raw materials:

2,4,4,4-tetrachlorobutyric acid chloride

isobutene

2,2,4,4,4-Pentachlorbuttersaeurechlorid

Downstream raw materials:

2,-(2',2',2'-trichloroethyl)-3,3-dimethylcyclobutanone

4-(2',2',2'-Trichloraethyl)-2-hydroxy-3,3-dimethylcyclobutanon

3-(2',2',2'-Trichloraethyl)-2-hydroxy-4,4-dimethylcyclobutanon

Refernces

• 1、 Martin,Greuter,Bellus. "Halogenated cyclobutanones as highly versatile precursors of pyrethroids: Syntheses via [2+2]-cycloadditions of haloketenes to 1,1-disubstituted ethylenes". . p. 64 - 77. Retrieved 2007/10/02.