Technology Process of Boronic acid, (3-methoxy-2,6-dimethylphenyl)- (9CI)
There total 5 articles about Boronic acid, (3-methoxy-2,6-dimethylphenyl)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,4-dimethyl-3-bromoanisole;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
With
Trimethyl borate;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
With
hydrogenchloride;
In
tetrahydrofuran; hexane; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / Heating / reflux
2.1: ethanol; potassium carbonate / 0.33 h / 20 °C
3.1: potassium carbonate / acetone / 5 h / Heating / reflux
4.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C
4.2: 20 °C
With
n-butyllithium; ethanol; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; hexane; dichloromethane; acetone;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: titanium tetrachloride / dichloromethane / 4 h / -78 - 20 °C
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / Heating / reflux
3.1: ethanol; potassium carbonate / 0.33 h / 20 °C
4.1: potassium carbonate / acetone / 5 h / Heating / reflux
5.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C
5.2: 20 °C
With
n-butyllithium; ethanol; titanium tetrachloride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; hexane; dichloromethane; acetone;
