(3-Methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane

Base Information

• Chemical Name: (3-Methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane
• CAS No.: 69861-02-5
• Molecular Formula: C17H38O6Si3
• Molecular Weight: 422.742
• UNII: 469MKT9U5Q
• DSSTox Substance ID: DTXSID201108518
• Nikkaji Number: J2.740.775G
• Mol file: 69861-02-5.mol

Synonyms:69861-02-5;469MKT9U5Q;(3-Methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane;UNII-469MKT9U5Q;methylbis(trimethylsiloxy)silylpropylglyceryl methacrylate;bis(trimethylsilyloxy)methylsilylpropylglycerol methacrylate;2-Propenoic acid, 2-methyl-, 2-hydroxy-3-(3-(1,3,3,3-tetramethyl-1-((trimethylsilyl)oxy)-1-disiloxanyl)propoxy)propyl ester;3-(3-(1,1,1,3,5,5,5-Heptamethyltrisiloxan-3-yl)propoxy)-2-hydroxypropyl methacrylate;SCHEMBL331864;DTXSID201108518;MFCD13195516;CS-0435512;[2-hydroxy-3-[3-[methyl-bis(trimethylsilyloxy)silyl]propoxy]propyl] 2-methylprop-2-enoate;N-(3-methacryloxy-2-hydroxypropyl)-3-aminopropyltriethoxysilane 50% in Ethanol;2-Hydroxy-3-[3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]-1-disiloxanyl]propoxy]propyl 2-methyl-2-propenoate

Chemical Property of (3-Methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.4084
• Boiling Point: 428.431oC at 760 mmHg
• PKA: 13.07±0.20(Predicted)
• Flash Point: 212.908oC
• PSA: 74.22000
• Density: 0.91
• LogP: 3.64830
• Storage Temp.: below 5° C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 14
• Exact Mass: 422.19761853
• Heavy Atom Count: 26
• Complexity: 440

Purity/Quality:

98%,99%, ^*data from raw suppliers

(3-METHACRYLOXY-2-HYDROXYPROPYL)METHYLBIS-(TRIMETHYLSILOXY)SILANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)OCC(COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C)O
• Uses: This monomer is commonly used in the formulation of research silicone hydrogel contact lenses and other research ophthalmic devices. Silicone monomers are preferred for the synthesis of research ophthalmic materials due to their high oxygen permeability.

Technology Process of (3-Methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane

There total 13 articles about (3-Methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

C13H33BrO4Si3 + potassium methacrylate (6900-35-2) → (3-methacryloxy-2-hydroxypropoxy)propyl-bis(trimethylsiloxy)methylsilane (69861-02-5)

Guidance literature:

With copper(l) iodide; In acetonitrile; at 25 ℃; for 24h; Temperature; Large scale;

Reference yield: 63.0%

3-allyloxy-2-hydroxypropyl methacrylate + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → (3-methacryloxy-2-hydroxypropoxy)propyl-bis(trimethylsiloxy)methylsilane (69861-02-5)

Guidance literature:

dihydrogen hexachloroplatinate; In hexanes; at 45 - 55 ℃; for 6h; Product distribution / selectivity;

Reference yield: 60.0%

poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) + 1-bis(trimethylsilyloxy)methylsilyl-3-(oxiran-2-ylmethoxy)-1-propanol (7422-52-8) → (3-methacryloxy-2-hydroxypropoxy)propyl-bis(trimethylsiloxy)methylsilane (69861-02-5)

Guidance literature:

poly(methacrylic acid); With lithium hydroxide; 4-methoxy-phenol; at 80 ℃;

1-bis(trimethylsilyloxy)methylsilyl-3-(oxiran-2-ylmethoxy)-1-propanol; at 20 - 90 ℃; for 20h; Product distribution / selectivity;

upstream raw materials:

poly(methacrylic acid)

1-bis(trimethylsilyloxy)methylsilyl-3-(oxiran-2-ylmethoxy)-1-propanol

lithium methacrylate

potassium methacrylate

Refernces

• 1、 -. "SILICONE COMPOUND PRODUCTION METHOD". Paragraph 0035-0040. . Retrieved 2021/10/13.
• 2、 -. "METHOD FOR PRODUCING SILOXANE". Paragraph 0050; 0052; 0054-0056. . Retrieved 2021/01/21.