Technology Process of cis-3-[4-(1,1-DiMethylheptyl)-2-(phenylMethoxy)phenyl]-cyclohexanol
There total 11 articles about cis-3-[4-(1,1-DiMethylheptyl)-2-(phenylMethoxy)phenyl]-cyclohexanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate;
In
tetrahydrofuran; methanol;
at -40 ℃;
for 1h;
DOI:10.1021/jm00367a013
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 78 percent / H2 / 10percent Pd/C / ethanol / 13 h / 2585.7 Torr
2: 100 percent / Br2 / CCl4 / 0.25 h / 30 °C
3: 1.) KH / 1.) DMF, -18 deg C, 15 min, 2.) 25 deg C, 30 min
4: Mg / tetrahydrofuran / 20 h / Heating
5: CuI / tetrahydrofuran / 0.5 h / -3 °C
6: 51 percent / NaBH4 / methanol; tetrahydrofuran / 1 h / -40 °C
With
sodium tetrahydroborate; copper(l) iodide; hydrogen; bromine; potassium hydride; magnesium;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; tetrachloromethane; ethanol;
DOI:10.1021/jm00367a013
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 57 percent / DMSO, NaOH / 4 h / 15 °C
2: 78 percent / H2 / 10percent Pd/C / ethanol / 13 h / 2585.7 Torr
3: 100 percent / Br2 / CCl4 / 0.25 h / 30 °C
4: 1.) KH / 1.) DMF, -18 deg C, 15 min, 2.) 25 deg C, 30 min
5: Mg / tetrahydrofuran / 20 h / Heating
6: CuI / tetrahydrofuran / 0.5 h / -3 °C
7: 51 percent / NaBH4 / methanol; tetrahydrofuran / 1 h / -40 °C
With
sodium hydroxide; sodium tetrahydroborate; copper(l) iodide; hydrogen; bromine; potassium hydride; magnesium; dimethyl sulfoxide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; tetrachloromethane; ethanol;
DOI:10.1021/jm00367a013
