2-Butenoic acid, 3-phenyl-, (Z)-

Base Information

• Chemical Name: 2-Butenoic acid, 3-phenyl-, (Z)-
• CAS No.: 704-79-0
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol file: 704-79-0.mol

Synonyms:

Chemical Property of 2-Butenoic acid, 3-phenyl-, (Z)-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Butenoic acid, 3-phenyl-, (Z)-

There total 31 articles about 2-Butenoic acid, 3-phenyl-, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(Z)-3-iodobut-2-enoic acid (34450-60-7) + phenylmagnesium bromide → (Z)-3-phenylbut-2-enoic acid (704-79-0)

Guidance literature:

phenylmagnesium bromide; With zinc dibromide; In diethyl ether; at 25 ℃;

(Z)-3-iodobut-2-enoic acid; dichloro bis(acetonitrile) palladium(II); In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; at 25 ℃; for 12h;

DOI:10.1055/s-2002-20971

Reference yield: 82.0%

ethyl (Z)-3-phenylbut-2-enoate (945-93-7,1504-72-9,13979-22-1) → (Z)-3-phenylbut-2-enoic acid (704-79-0)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 20 ℃; for 16h;

DOI:10.1021/jacs.5b12081

Reference yield: 56.0%

diphenyl(trifluoromethanesulfonato)-λ3-iodane + 2-butenoic acid (3724-65-0) → (Z)-3-phenylbut-2-enoic acid (704-79-0)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) triflimide; Trimethylacetic acid; In cyclohexane; at 100 ℃; for 12h; regioselective reaction; Schlenk technique; Molecular sieve; Inert atmosphere;

DOI:10.1039/c6ob01145d

upstream raw materials:

acetophenone

carbon dioxide

N,N-dimethyl-aniline

isopropenylbenzene

Downstream raw materials:

3-phenylbutyric acid

β-methyl-4-nitrocinnamic acid

2,3-dibromo-3-phenyl-butyric acid

isopropenylbenzene

Refernces

• 1、 Wu, Jichang,Mou, Chengli,Chi, Yonggui Robin. "Construction of Multi-Substituted Benzenes via NHC-Catalyzed Reactions of Carboxylic Esters". . p. 333 - 337. Retrieved 2018/03/07.
• 2、 Gopi Krishna Reddy, Alavala,Satyanarayana, Gedu. "Metal-Free Domino One-Pot Decarboxylative Cyclization of Cinnamic Acid Esters: Synthesis of Functionalized Indanes". . p. 12212 - 12222. Retrieved 2016/12/23.