4-CHLOROBENZOFURAZAN

Base Information

• Chemical Name: 4-CHLOROBENZOFURAZAN
• CAS No.: 7116-16-7
• Molecular Formula: C6H3ClN2O
• Molecular Weight: 154.556
• Hs Code.: 29349990
• Mol file: 7116-16-7.mol

Synonyms:4-CHLOROBENZOFURAZAN;Chlorobenzofurazan;4-CHLOROBENZOFURAZAN 98+%;4-Chloro-2,1,3-benzoxadiazole;4-chloro-2,1,3-benzoxodiazole;4-Chlorobenzofurazane;4-chlorobenzo[c][1,2,5]oxadiazole;2,1,3-Benzoxadiazole, 4-chloro-

Chemical Property of 4-CHLOROBENZOFURAZAN

Chemical Property:

• Vapor Pressure: 0.1mmHg at 25°C
• Melting Point: 82°C
• Refractive Index: 1.634
• Boiling Point: 230.3 °C at 760 mmHg
• PKA: -1.92±0.45(Predicted)
• Flash Point: 93.1 °C
• PSA: 38.92000
• Density: 1.475 g/cm³
• LogP: 1.87620
• Solubility.: almost transparency in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Chloro-2,1,3-benzoxadiazole ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLOROBENZOFURAZAN

There total 4 articles about 4-CHLOROBENZOFURAZAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2,6-dichloronitrobenzene (601-88-7) → 4-chloro-2,1,3-benzoxadiazole (7116-16-7)

Guidance literature:

With sodium azide; In dimethyl sulfoxide; at 20 - 120 ℃; for 3.08h;

DOI:10.3762/bjoc.13.76

Reference yield:

2,6-dichloronitrosobenzene (1194-66-7) → 4-chloro-2,1,3-benzoxadiazole (7116-16-7)

Guidance literature:

Multistep reaction; (i) NaN₃, DMSO, (ii) (heating);

DOI:10.1021/jm00308a027

Reference yield:

2,6-Dichloroaniline (608-31-1) → 4-chloro-2,1,3-benzoxadiazole (7116-16-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 23 °C / Inert atmosphere

2: sodium azide / dimethyl sulfoxide / 2.5 h / 23 °C / Inert atmosphere

With sodium azide; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.tetlet.2011.02.111

upstream raw materials:

2,6-dichloronitrosobenzene

2,6-Dichloroaniline

2,6-dichloronitrobenzene

Downstream raw materials:

NBD chloride

C₁₅H₁₄N₄O₄

2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose

(S)-1-(7-Nitro-benzo[1,2,5]oxadiazol-4-yl)-pyrrolidine-2-carboxylic acid

Refernces

• 1、 Jung, Michael E.,Dong, Timothy A.,Cai, Xiaolu. "Improved synthesis of 4-amino-7-nitrobenz-2,1,3-oxadiazoles using NBD fluoride (NBD-F)". body text. p. 2533 - 2535. Retrieved 2011/06/21.