9-AZABICYCLO[3,3,1]NONANE

Base Information

• Chemical Name: 9-AZABICYCLO[3,3,1]NONANE
• CAS No.: 280-97-7
• Molecular Formula: C8H15 N
• Molecular Weight: 125.214
• Hs Code.: 2933990090
• Mol file: 280-97-7.mol

Synonyms:Granatanine;N-Demethylgranatane; Norgranatane

Chemical Property of 9-AZABICYCLO[3,3,1]NONANE

Chemical Property:

• Melting Point: 322-326 °C (decomp)
• Boiling Point: 55-56 °C(Press: 0.1 Torr)
• PKA: 11.80±0.20(Predicted)
• PSA: 12.03000
• Density: 0.915±0.06 g/cm3(Predicted)
• LogP: 2.00980

Purity/Quality:

98%,99%, ^*data from raw suppliers

9-Azabicyclo[3.3.1]nonane hydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 22-36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 9-Azabicyclo[3.3.1]nonane is used as a reactant in the preparation of azabicyclo[3.3.1]nonane N-oxyl.

Technology Process of 9-AZABICYCLO[3,3,1]NONANE

There total 17 articles about 9-AZABICYCLO[3,3,1]NONANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

9-benzyl-9-azabicyclo<3.3.1>nonane (57659-50-4) → 9-aza-bicyclo[3.3.1]nonane (280-97-7)

Guidance literature:

With methanol; 20% palladium hydroxide-activated charcoal; hydrogen; at 50 ℃; for 3h; under 30003 Torr; Autoclave;

Reference yield: 48.0%

9-methyl-9-aza-bicyclo[3.3.1]nonane (491-25-8) → 9-aza-bicyclo[3.3.1]nonane (280-97-7) + 9-formyl-9-aza-bicyclo[3.3.1]nonane (33490-93-6)

Guidance literature:

With ruthenium tetroxide; In tetrachloromethane; for 3h;

DOI:10.1002/ardp.19843170712

Reference yield: 29.5%

9-azabicyclo[3.3.1]nonan-3-one → 9-aza-bicyclo[3.3.1]nonane (280-97-7)

Guidance literature:

With hydrazine hydrate; potassium hydroxide; In 2,2'-[1,2-ethanediylbis(oxy)]bisethanol; at 215 ℃; under 11251.1 Torr; Autoclave;

upstream raw materials:

9-methyl-9-aza-bicyclo[3.3.1]nonane

9-benzyl-9-azabicyclo<3.3.1>nonane

exo-9-methyl-9-azabicyclo[3.3.1]nonan-3-ol

9-benzyl-9-azabicyclo[3.3.1]nonan-3-one

Downstream raw materials:

9-ethyl-9-azabicyclo<3.3.1>nonane

Benzoyloxy-9-borabicyclo<3.3.1>nonane

C₃₅H₄₂N₂O₄

Refernces

• 1、 -. "Preparation method of 9-azabicyclo [3.3. 1] nonyl-N-oxygen free radical". Paragraph 0029-0030. . Retrieved 2021/06/02.
• 2、 -. "Preparation method of 2-azanoradamantane-N-Oxyl". Paragraph 0074-0076. . Retrieved 2017/06/02.