3,4'-Difluoro-1,1'-biphenyl

Base Information

• Chemical Name: 3,4'-Difluoro-1,1'-biphenyl
• CAS No.: 72093-44-8
• Molecular Formula: C12H8F2
• Molecular Weight: 190.192
• DSSTox Substance ID: DTXSID501309937
• Nikkaji Number: J3.039.928E
• Mol file: 72093-44-8.mol

Synonyms:3,4'-Difluoro-1,1'-biphenyl;72093-44-8;SCHEMBL777750;DTXSID501309937

Chemical Property of 3,4'-Difluoro-1,1'-biphenyl

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 190.05940658
• Heavy Atom Count: 14
• Complexity: 173

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)F)C2=CC=C(C=C2)F

Technology Process of 3,4'-Difluoro-1,1'-biphenyl

There total 1 articles about 3,4'-Difluoro-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluorobenzene (462-06-6) → 2,4'-difluorodiphenyl (2285-28-1) + 3,4'-difluorobiphenyl (72093-44-8) + 4,4'-difluorobiphenyl (398-23-2) + 2,3'-difluorodiphenyl (80254-73-5)

Guidance literature:

With thallium(III) trifluoroacetate; palladium diacetate; at 70 ℃; for 40h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(01)91964-7

Reference yield: 70.0%

3,4'-difluorobiphenyl (72093-44-8) + bis(pinacol)diborane (73183-34-3) → C24H32B2O4

Guidance literature:

With chlorobis(tricyclohexylphosphine)copper(I); cesium fluoride; In toluene; at 80 ℃; for 24h;

DOI:10.1021/acscatal.7b01448

upstream raw materials:

fluorobenzene

Refernces