CIS-3,5-DIMETHYLCYCLOHEXANONE

Base Information

• Chemical Name: CIS-3,5-DIMETHYLCYCLOHEXANONE
• CAS No.: 7214-52-0
• Molecular Formula: C8H14O
• Molecular Weight: 126.199
• Mol file: 7214-52-0.mol

Synonyms:3,5-dimethyl-cyclohexanone;(3R,5S)-3,5-dimethylcyclohexanone;cis-3,5-Dimethyl-cyclohexanon;Cyclohexanone,3,5-dimethyl-,(3R,5S)-rel;cis-3,5-dimethylcyclohexanone;cis-1.3-Dimethyl-cyclohexanon-(5);cyclohexanone,3,5-dimethyl-,(3R,5S);syn-3,5-dimethylcyclohexanone;

Chemical Property of CIS-3,5-DIMETHYLCYCLOHEXANONE

Chemical Property:

• PSA: 17.07000
• LogP: 2.01160

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: This compound is useful in biological studies in the bioprospecting of bioactive metabolites from from Monochaetia karstenii.

Technology Process of CIS-3,5-DIMETHYLCYCLOHEXANONE

There total 41 articles about CIS-3,5-DIMETHYLCYCLOHEXANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-dimethyl-2-cyclohexen-1-one (1123-09-7) → 3,5-dimethyl-cyclohexanone (7214-52-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In isopropyl alcohol; for 2h;

DOI:10.1016/j.tet.2015.11.057

Reference yield: 91.0%

(R)-5-methyl-cyclohex-2-enone (54307-74-3,15466-88-3) → 3,5-dimethyl-cyclohexanone (7214-52-0)

Guidance literature:

In diethyl ether; at -20 ℃;

DOI:10.1016/S0040-4039(00)95911-2

Reference yield: 79.0%

cis-2-carbomethoxy-3,5-dimethylcyclohexanone → 3,5-dimethyl-cyclohexanone (7214-52-0)

Guidance literature:

With sodium chloride; In dimethyl sulfoxide; at 170 ℃; for 2h;

DOI:10.1002/chem.200400459

upstream raw materials:

(R)-5-methyl-cyclohex-2-enone

dimethyl zinc(II)

5-methylcyclohex-2-en-1-one

trimethylaluminum

Downstream raw materials:

1-hydroxy-3r,5c-dimethyl-cyclohexane-ξ-carbonitrile

(+/-)-trans-1.3-dimethyl-cyclohexanone-⁽⁵⁾-semicarbazone

2,4-Dimethyl-5,6-dioxoheptamsaeure-5-phenylhydrazon

((3S,5R)-3,5-Dimethyl-cyclohex-1-enyloxy)-trimethyl-silane

Refernces

• 1、 Dickson, Emma,Pilkington, Lisa I.,Brimble, Margaret A.,Barker, David. "Enantioselective synthesis of BE ring analogues of methyllycaconitine". . p. 400 - 414. Retrieved 2015/12/31.
• 2、 Holan, Martin,Jahn, Ullrich. "Anaerobic nitroxide-catalyzed oxidation of alcohols using the NO +/NO· redox pair". supporting information. p. 58 - 61. Retrieved 2014/01/23.