1-Bromo-2-fluoropropane

Base Information

• Chemical Name: 1-Bromo-2-fluoropropane
• CAS No.: 1871-72-3
• Molecular Formula: C3H6 Br F
• Molecular Weight: 140.983
• Hs Code.: 2903799090
• DSSTox Substance ID: DTXSID90862770
• Nikkaji Number: J573.210G
• Mol file: 1871-72-3.mol

Synonyms:1-bromo-2-fluoropropane;1871-72-3;Propane, 1-bromo-2-fluoro-;1-BROMO-2-FLUORO-PROPANE;SCHEMBL989728;DTXSID90862770;F2147-5481

Chemical Property of 1-Bromo-2-fluoropropane

Chemical Property:

• Vapor Pressure: 81.4mmHg at 25°C
• Boiling Point: 84.2°Cat760mmHg
• Flash Point: 6°C
• PSA: 0.00000
• Density: 1.452g/cm³
• LogP: 1.73930
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 139.96369
• Heavy Atom Count: 5
• Complexity: 22.9

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CBr)F

Technology Process of 1-Bromo-2-fluoropropane

There total 3 articles about 1-Bromo-2-fluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

1,3-dibromo-propane (109-64-8) → 1-Bromo-3-fluoropropane (352-91-0) + 1-bromo-2-fluoro-propane (1871-72-3) + 1,2-difluoro-3-bromopropane (111483-20-6)

Guidance literature:

With bromine trifluoride; In various solvent(s); at 10 - 20 ℃; for 4h;

Reference yield:

propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) → 1,2-Dibromopropane (78-75-1) + 1-bromo-2-fluoro-propane (1871-72-3)

Guidance literature:

With sulfur tetrafluoride; hydrogen fluoride; bromine; at 20 ℃; for 24h; Yield given. Yields of byproduct given;

Reference yield:

1,3-dibromo-propane (109-64-8) → 1-Bromo-3-fluoropropane (352-91-0) + 1-bromo-2-fluoro-propane (1871-72-3)

Guidance literature:

With chlorine monofluoride; at 20 - 40 ℃;

upstream raw materials:

propene

1,3-dibromo-propane

Downstream raw materials:

2,2-Dimethyl-propionic acid 3-benzyl-8-cyclopentyl-1-(2-fluoro-propyl)-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-ylmethyl ester

1-(2-fluoropropyl)-4-phenylpiperazine

Refernces

• 1、 Chuvatkin, N. N.,Kartashov, A. V.,Morozova, T. V.,Boguslavskaya, L. S.. "REACTIONS OF HALOGENS FLUORIDES. VIII. SUBSTITUTIVE FLUORINATION OF BROMINE-CONTAINING ALKANES AND ESTERS WITH BROMINE TRIFLUORIDE". . p. 237 - 242. Retrieved 2007/10/02.