Ethanedione, bis[4-(trifluoromethyl)phenyl]-

Base Information

• Chemical Name: Ethanedione, bis[4-(trifluoromethyl)phenyl]-
• CAS No.: 73790-20-2
• Molecular Formula: C16H8F6O2
• Molecular Weight: 346.229
• Mol file: 73790-20-2.mol

Synonyms:1,2-Bis[4-(trifluoromethyl)phenyl]-1,2-ethanedione;1,2-Bis(4-trifluoromethylphenyl)-ethan-1,2-dione;4,4'-Bis(trifluoromethyl)benzil;Ethanedione,bis[4-(trifluoromethyl)phenyl];1,2-bis(p-trifluoromethylphenyl)ethanedione;1,2-bis(4-(trifluoromethyl)phenyl)ethane-1,2-dione;

Chemical Property of Ethanedione, bis[4-(trifluoromethyl)phenyl]-

Chemical Property:

• Melting Point: 134-136 °C(Solv: ethanol (64-17-5))
• Boiling Point: 378.6±42.0 °C(Predicted)
• PSA: 34.14000
• Density: 1.399±0.06 g/cm3(Predicted)
• LogP: 4.78980

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanedione, bis[4-(trifluoromethyl)phenyl]-

There total 15 articles about Ethanedione, bis[4-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,2-bis[4-(trifluoromethyl)phenyl]-2-hydroxyethanone (73627-36-8) → 4,4'-bis(trifluoromethyl)benzil (73790-20-2)

Guidance literature:

With ammonium nitrate; copper diacetate; acetic acid; for 90h; Heating;

DOI:10.1016/j.bmc.2007.03.012

Reference yield: 90.0%

1,2-bis(4-(trifluoromethyl)phenyl)ethyne (119757-51-6) → 4,4'-bis(trifluoromethyl)benzil (73790-20-2)

Guidance literature:

With iodine; dimethyl sulfoxide; at 155 ℃; for 14h; Inert atmosphere;

DOI:10.1039/c2cc33892k

Reference yield: 89.4%

4-(trifluoromethyl)benzylic alcohol (349-95-1) → 4,4'-bis(trifluoromethyl)benzil (73790-20-2)

Guidance literature:

With oxygen; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; copper(I) bromide; sodium nitrite; In acetonitrile; at 75 ℃; for 14h;

upstream raw materials:

methyl 4-(trifluoromethyl)benzoate

p-trifluoromethylphenyl bromide

oxalic acid diethyl ester

1,2-bis[4-(trifluoromethyl)phenyl]-2-hydroxyethanone

Downstream raw materials:

C₃₁H₁₆Br₂F₆O

4-oxo-2-(4-(trifluoromethyl)benzoyl)-4-(4-(trifluoromethyl)phenyl)butanenitrile

Refernces

• 1、 Chen, Yang,Fan, Jian,Huang, Yuting,Li, Yaowen,Sun, Bangjin. "Fused-ring acceptors based on quinoxaline unit for highly efficient single-junction organic solar cells with low charge recombination". . . Retrieved 2021/07/21.
• 2、 -. "Preparation method of bibenzoyl compound and application". Paragraph 0021-0023. . Retrieved 2019/11/20.