N-(1-Methylpropyl)hexadecanamide

Base Information

• Chemical Name: N-(1-Methylpropyl)hexadecanamide
• CAS No.: 74058-69-8
• Molecular Formula: C₂₀H₄₁NO
• Molecular Weight: 311.552
• DSSTox Substance ID: DTXSID201303011
• Mol file: 74058-69-8.mol

Synonyms:N-(1-Methylpropyl)hexadecanamide;SCHEMBL2058975;URHNAYNJPDEERP-UHFFFAOYSA-N;DTXSID201303011;74058-69-8

Chemical Property of N-(1-Methylpropyl)hexadecanamide

Chemical Property:

• PSA: 29.10000
• LogP: 6.77330
• XLogP3: 8.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 16
• Exact Mass: 311.318814931
• Heavy Atom Count: 22
• Complexity: 240

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)NC(C)CC

Technology Process of N-(1-Methylpropyl)hexadecanamide

There total 5 articles about N-(1-Methylpropyl)hexadecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

SEC-BUTYLAMINE (33966-50-6) + C28H40N2O2 (100663-86-3) → hexadecanoic acid N-(sec-butyl)amide (74058-69-8) + (E)-2-pyridylphenyl ketoxime (14178-31-5)

Guidance literature:

In dichloromethane; for 24h; Ambient temperature;

DOI:10.1246/cl.1985.701

Reference yield: 97.0%

SEC-BUTYLAMINE (33966-50-6) + 1-(2-Thioxo-thiazolidin-3-yl)-hexadecan-1-one (74058-64-3) → hexadecanoic acid N-(sec-butyl)amide (74058-69-8)

Guidance literature:

In dichloromethane; for 0.5h; Product distribution; Ambient temperature; monitored aminolysis of further 3-acyl-1,3-thiazolidine-2-ones; further amino compounds in further solvents;

Reference yield:

SEC-BUTYLAMINE (33966-50-6) + 1-hexadecylcarboxylic acid (57-10-3) → hexadecanoic acid N-(sec-butyl)amide (74058-69-8)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1016/j.phytochem.2005.01.012

upstream raw materials:

SEC-BUTYLAMINE

1-(2-Thioxo-thiazolidin-3-yl)-hexadecan-1-one

C₂₈H₄₀N₂O₂

1-hexadecylcarboxylic acid

Refernces

• 1、 Miyasaka, Tadayo,Noguchi, Shunsaku. "HIGH CHEMOSELECTIE SYNTHESIS OF CARBOXAMIDES BY USING SYN-PHENYLPYRIDYL-O-ACYL OXIMES(PPKO)". . p. 701 - 704. Retrieved 2007/10/02.
• 2、 Nagao, Yoshimitsu,Seno, Kaoru,Kawabata, Kohji,Miyasaka, Tadayo,Takao, Sachiko,Fujita, Eiichi. "MONITORED AMINOLYSIS OF 3-ACYLTHIAZOLIDINE-2-THIONE : A NEW CONVENIENT SYNTHESIS OF AMIDE". . p. 841 - 844. Retrieved 2007/10/02.