3-Pyrazolidinecarboxylic acid, 5-oxo-2-phenyl-, ethyl ester

Base Information

• Chemical Name: 3-Pyrazolidinecarboxylic acid, 5-oxo-2-phenyl-, ethyl ester
• CAS No.: 7426-59-7
• Molecular Formula: C12H14N2O3
• Molecular Weight: 234.255
• Mol file: 7426-59-7.mol

Synonyms:

Chemical Property of 3-Pyrazolidinecarboxylic acid, 5-oxo-2-phenyl-, ethyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyrazolidinecarboxylic acid, 5-oxo-2-phenyl-, ethyl ester

There total 2 articles about 3-Pyrazolidinecarboxylic acid, 5-oxo-2-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.4%

phenylhydrazine (100-63-0) + Diethyl maleate (141-05-9) → 5-oxo-2-phenyl-pyrazolidine-3-carboxylic acid ethyl ester (7426-59-7)

Guidance literature:

phenylhydrazine; With sodium; In ethanol; at 78 ℃; for 0.1h;

Diethyl maleate; In ethanol; at 78 ℃; for 4h;

Reference yield:

→ 5-oxo-2-phenyl-pyrazolidine-3-carboxylic acid ethyl ester (7426-59-7)

Guidance literature:

1-Phenyl-3-oxo-pyrazolidin-carbonsaeure-(5) u. A.(H2SO4);

Reference yield: 65.21%

5-oxo-2-phenyl-pyrazolidine-3-carboxylic acid ethyl ester (7426-59-7) → C12H13ClN2O2

Guidance literature:

With trichlorophosphate; In acetonitrile; at 85 ℃; for 5h;

upstream raw materials:

phenylhydrazine

Diethyl maleate

Downstream raw materials:

C₁₀H₇ClN₂O₂

Refernces