Methyl(1-naphtyl)(phenyl)silane

Base Information

• Chemical Name: Methyl(1-naphtyl)(phenyl)silane
• CAS No.: 7427-12-5
• Molecular Formula: C17H16Si
• Molecular Weight: 248.4
• Mol file: 7427-12-5.mol

Synonyms:methyl-naphthalen-1-yl-phenyl-silane;

Chemical Property of Methyl(1-naphtyl)(phenyl)silane

Chemical Property:

• PSA: 0.00000
• LogP: 4.61500

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl(1-naphtyl)(phenyl)silane

There total 16 articles about Methyl(1-naphtyl)(phenyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(S)-(-)-[(-)-menthyloxy](1-naphthyl)methylphenylsilane (35742-37-1) → (+)-methyl-(α-naphthyl)-phenylsilane (1025-08-7,1025-09-8,7427-12-5,17037-10-4)

Guidance literature:

With lithium aluminium tetrahydride; In dibutyl ether; at 80 - 90 ℃; for 18h;

Reference yield: 75.0%

1-Bromonaphthalene (90-11-9) + dichloromethylphenylsilane (149-74-6) → methyl-naphthalen-1-yl-phenyl-silane (7427-12-5)

Guidance literature:

1-Bromonaphthalene; With n-butyllithium; In diethyl ether; hexane; at -40 ℃; for 1h; Schlenk technique; Inert atmosphere;

dichloromethylphenylsilane; In diethyl ether; hexane; at 20 ℃; for 6h; Schlenk technique; Inert atmosphere;

With lithium aluminium tetrahydride; In diethyl ether; hexane; at 20 ℃; for 12h;

DOI:10.1002/chem.201502746

Reference yield: 56.0%

→ (+)-methyl-(α-naphthyl)-phenylsilane (1025-08-7,1025-09-8,7427-12-5,17037-10-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Ambient temperature;

DOI:10.1016/S0022-328X(00)86747-9

upstream raw materials:

methoxy(methyl)(1-naphthyl)phenylsilane

tetrahydrofuran

CH₃(C₆H₅)(C₁₀H₇)SiGe(C₆H₅)3

methyl magnesium iodide

Downstream raw materials:

Methylphenyl-1-naphthylallylsilan

1-Naphthylphenylmethyldibromomethylsilan

(+)α-naphthylphenylmethyloctylsilane

naphthalene

Refernces

• 1、 Lesbani, Aldes,Kondo, Hitoshi,Yabusaki, Yusuke,Nakai, Misaki,Yamanoi, Yoshinori,Nishihara, Hiroshi. "Integrated palladium-catalyzed arylation of heavier groupa 14 hydrides". supporting information; experimental part. p. 13519 - 13527. Retrieved 2011/02/24.
• 2、 Tobita, Hiromi,Shiozawa, Rie,Ogino, Hiroshi. "Reaction of silyl(carbonyl)iron complexes with liAlH4 giving methylsilanes: Reduction of a carbonyl ligand and coupling with a silyl group". . p. 805 - 806. Retrieved 2007/10/03.